Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 17/20 | 0.39 |
| ▸ | ACACA | Q13085 | 15/20 | 0.39 |
| ▸ | IKBKB | O14920 | 2/20 | 0.35 |
| ▸ | CHUK | O15111 | 2/20 | 0.35 |
| ▸ | IKBKG | Q9Y6K9 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3497601 | 0.98 | CYP2C9 (0.40) | CYP2C9ACACBACACAIKBKBCHUK | |
| SCHEMBL3498033 | 0.92 | ACACB (0.41) | CYP2C9ACACBACACAIKBKBCHUK | |
| SCHEMBL3496515 | 0.91 | ACACB (0.46) | CYP2C9ACACBACACAIKBKBCHUK | |
| SCHEMBL3498667 | 0.86 | ACACB (0.43) | CYP2C9ACACBACACAIKBKBCHUK | |
| SCHEMBL3496815 | 0.85 | ACACB (0.54) | CYP2C9ACACBACACA | |
| SCHEMBL4722214 | 0.84 | ACACB (0.44) | CYP2C9ACACBACACAIKBKBCHUK | |
| SCHEMBL3497216 | 0.84 | ACACB (0.44) | CYP2C9ACACBACACAIKBKBCHUK | |
| SCHEMBL13312728 | 0.83 | ACACB (0.44) | CYP2C9ACACBACACAIKBKBCHUK | |
| SCHEMBL3496627 | 0.82 | ACACB (0.52) | CYP2C9ACACBACACA | |
| SCHEMBL4724543 | 0.82 | ACACB (0.45) | CYP2C9ACACBACACAIKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160255-A1 | SPIRO-CYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160255-A1 | SPIRO-CYCLIC COMPOUND | ACACA, CPT1B, PC | CYP2C9 1717/4885ACACB 6/4885ACACA 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.