Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR34 | Q9UPC5 | 8/20 | 0.55 |
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.43 |
| ▸ | ITGAV | P06756 | 2/20 | 0.43 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.42 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3499675 | 1.00 | GPR34 (0.55) | GPR34GPR132PTPN1ALOX5ALOX5AP | |
| SCHEMBL3497265 | 0.93 | CDK2 (0.47) | GPR34ALOX5ALOX5AP | |
| SCHEMBL3497262 | 0.93 | CDK2 (0.47) | GPR34ALOX5ALOX5AP | |
| SCHEMBL3499647 | 0.92 | GPR34 (0.54) | GPR34GPR132PTPN1ITGB3ITGB1 | |
| SCHEMBL3499645 | 0.92 | GPR34 (0.54) | GPR34GPR132PTPN1ITGB3ITGB1 | |
| SCHEMBL3498605 | 0.92 | GPR34 (0.62) | GPR34GPR132PTPN1PTPN2CDC25B | |
| SCHEMBL3497834 | 0.92 | GPR34 (0.62) | GPR34GPR132PTPN1PTPN2CDC25B | |
| SCHEMBL3498320 | 0.91 | GPR34 (0.58) | GPR34GPR132PTPN1PTPN2CDC25B | |
| SCHEMBL3498322 | 0.91 | GPR34 (0.58) | GPR34GPR132PTPN1PTPN2CDC25B | |
| SCHEMBL3500080 | 0.91 | GPR34 (0.53) | GPR34GPR132PTPN1ITGB3ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-27 | — | — | US | disclosed |
| EP-1849465-A1 | AGENT FOR CONTROLLING FUNCTION OF GPR34 RECEPTOR | Takeda Pharmaceutical Company Limited (JP) | 2007-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | GPR34, GPR4, GPR6 | GPR34 1/4885GPR132 13/4885PTPN1 3494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.