Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 15/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 13/20 | 0.57 |
| ▸ | CDC25B | P30305 | 13/20 | 0.57 |
| ▸ | PTPN6 | P29350 | 9/20 | 0.52 |
| ▸ | GPR34 | Q9UPC5 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3499724 | 1.00 | PTPN1 (0.57) | PTPN1PTPN2CDC25BPTPN6GPR34 | |
| SCHEMBL5276284 | 0.93 | PTPN1 (0.48) | PTPN1PTPN2CDC25BPTPN6GPR34 | |
| SCHEMBL5276292 | 0.93 | PTPN1 (0.48) | PTPN1PTPN2CDC25BPTPN6GPR34 | |
| SCHEMBL3498605 | 0.91 | GPR34 (0.62) | PTPN1PTPN2CDC25BGPR34 | |
| SCHEMBL3497834 | 0.91 | GPR34 (0.62) | PTPN1PTPN2CDC25BGPR34 | |
| SCHEMBL5274701 | 0.90 | PTPN1 (0.59) | PTPN1PTPN2CDC25BPTPN6GPR34 | |
| SCHEMBL5274696 | 0.90 | PTPN1 (0.59) | PTPN1PTPN2CDC25BPTPN6GPR34 | |
| SCHEMBL3498322 | 0.90 | GPR34 (0.58) | PTPN1PTPN2CDC25BGPR34 | |
| SCHEMBL3498320 | 0.90 | GPR34 (0.58) | PTPN1PTPN2CDC25BGPR34 | |
| SCHEMBL3499645 | 0.89 | GPR34 (0.54) | PTPN1PTPN2CDC25BGPR34 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-27 | — | — | US | disclosed |
| EP-1849465-A1 | AGENT FOR CONTROLLING FUNCTION OF GPR34 RECEPTOR | Takeda Pharmaceutical Company Limited (JP) | 2007-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | GPR34, GPR4, GPR6 | PTPN1 3494/4885PTPN2 3461/4885CDC25B 3545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.