Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 8/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | CLK1 | P49759 | 1/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.52 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26698252 | 0.78 | IMPDH2 (0.63) | IMPDH2CLK1CDK5CDK5R1DYRK1A | |
| SCHEMBL8115984 | 0.74 | IMPDH2 (0.59) | IMPDH2MAPK1HSD17B10PIK3CD | |
| SCHEMBL17179567 | 0.73 | IMPDH2 (0.57) | IMPDH2HSD17B10CLK1CDK5CDK5R1 | |
| SCHEMBL238277 | 0.72 | IMPDH2 (1.00) | IMPDH2MAPK1HSD17B10DYRK1AGSK3B | |
| SCHEMBL29431212 | 0.72 | IMPDH2 (1.00) | IMPDH2MAPK1HSD17B10DYRK1AGSK3B | |
| SCHEMBL4788625 | 0.71 | IMPDH2 (0.55) | IMPDH2MAPK1HSD17B10CDK5 | |
| SCHEMBL1720510 | 0.70 | PARP1 (0.72) | IMPDH2MAPK1HSD17B10DYRK1AGSK3B | |
| SCHEMBL31521724 | 0.70 | IMPDH2 (0.52) | IMPDH2CLK1CDK5CDK5R1DYRK1A | |
| SCHEMBL18662633 | 0.70 | DYRK1A (0.64) | IMPDH2CLK1CDK5CDK5R1DYRK1A | |
| SCHEMBL857678 | 0.69 | IKBKE (0.64) | IMPDH2MAPK1HSD17B10CLK1CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100133117-A1 | METHODS FOR ELECTROCHEMICAL DETECTION/QUANTIFICATION OF A NUCLEIC ACID | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-06-03 | — | — | US | disclosed |
| WO-2008097190-A1 | METHODS OF ELECTRICALLY DETECTING A NUCLEIC ACID BY MEANS OF AN ELECTRODE PAIR | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008018833-A1 | METHODS FOR ELECTROCHEMICAL DETECTION/QUANTIFICATION OF A NUCLEIC ACID | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2008-02-14 | — | — | WO | disclosed |