Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 6/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | GSK3B | P49841 | 2/20 | 0.68 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.68 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.62 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.61 |
| ▸ | TDO2 | P48775 | 4/20 | 0.60 |
| ▸ | PIM1 | P11309 | 1/20 | 0.54 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29431212 | 1.00 | IMPDH2 (1.00) | IMPDH2MAPK1HSD17B10GSK3BDYRK1A | |
| SCHEMBL28377762 | 0.86 | NR4A2 (0.81) | IMPDH2MAPK1HSD17B10MAPTSMN1; SMN2 | |
| 3-Phenylindole SCHEMBL29609072 | 0.84 | IMPDH2 (0.71) | IMPDH2MAPK1HSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL28416622 | 0.84 | NR4A2 (0.78) | IMPDH2MAPK1HSD17B10MAPTSMN1; SMN2 | |
| 3-Phenylindole SCHEMBL84056 | 0.84 | IMPDH2 (0.71) | IMPDH2MAPK1HSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL27744407 | 0.82 | IMPDH2 (0.68) | IMPDH2MAPK1HSD17B10GSK3BDYRK1A | |
| SCHEMBL25421202 | 0.81 | DYRK1A (1.00) | IMPDH2MAPK1HSD17B10GSK3BDYRK1A | |
| SCHEMBL30461701 | 0.81 | DYRK1A (1.00) | IMPDH2MAPK1HSD17B10GSK3BDYRK1A | |
| SCHEMBL22460246 | 0.81 | IMPDH2 (0.67) | IMPDH2MAPK1HSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL13183827 | 0.81 | IMPDH2 (0.65) | IMPDH2MAPK1HSD17B10GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 339 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3843845-B1 | INHIBITION OF PROTEIN KINASES TO TREAT FRIEDREICH ATAXIA | UNIV MASSACHUSETTS (US) | 2026-03-11 | — | — | EP | claimed |
| US-12281308-B2 | Inhibition of protein kinases to treat Friedreich ataxia | UNIVERSITY OF MASSACHUSETTS (US) | 2025-04-22 | — | — | US | claimed |
| EP-4319877-A1 | COMPOSITIONS AND METHODS FOR TREATING SPINAL CORD INJURY AND SYNAPTIC DYSFUNCTION | Mitz, Howard (US) | 2024-02-14 | — | — | EP | claimed |
| WO-2022216537-A1 | COMPOSITIONS AND METHODS FOR TREATING SPINAL CORD INJURY AND SYNAPTIC DYSFUNCTION | MITZ HOWARD (US) | 2022-10-13 | — | — | WO | claimed |
| US-20210292766-A1 | Inhibition of Protein Kinases to Treat Friedreich Ataxia | UNIVERSITY OF MASSACHUSETTS | 2021-09-23 | — | — | US | claimed |
| EP-3843845-A1 | INHIBITION OF PROTEIN KINASES TO TREAT FRIEDREICH ATAXIA | University Of Massachusetts (US) | 2021-07-07 | — | — | EP | claimed |
| WO-2020047229-A1 | INHIBITION OF PROTEIN KINASES TO TREAT FRIEDREICH ATAXIA | UNIVERSITY OF MASSACHUSETTS (US) | 2020-03-05 | — | — | WO | claimed |
| US-20190328721-A1 | METHOD OF ACTIVATING DENDRITIC CELLS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2019-10-31 | — | — | US | claimed |
| EP-2377544-B1 | PHARMACEUTICAL COMPOSITION CONTAINING ANGIOTENSIN-(1-9) FOR CARDIOVASCULAR, PULMONARY AND/OR CEREBRAL TREATMENT | PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE (CL) | 2014-10-22 | — | — | EP | claimed |
| EP-2408903-B1 | CULTURE OF PLURIPOTENT AND MULTIPOTENT CELLS ON MICROCARRIERS | AGENCY SCIENCE TECH & RES (SG) | 2014-08-06 | — | — | EP | claimed |
| WO-2014053709-A1 | A METHOD FOR CULTURING STEM CELLS | GLYKOS FINLAND OY (FI) | 2014-04-10 | — | — | WO | claimed |
| US-20130123345-A1 | METHOD OF TREATING A VIRAL INFECTION DYSFUNCTION BY DISRUPTING AN ADENOSINE RECEPTOR PATHWAY | THE OHIO STATE UNIVERSITY (US) | 2013-05-16 | — | — | US | claimed |
| WO-2012012736-A2 | METHOD OF TREATING A VIRAL INFECTION DYSFUNCTION BY DISRUPTING AN ADENOSINE RECEPTOR PATHWAY | THE OHIO STATE UNIVERSITY (US) | 2012-01-26 | — | — | WO | claimed |
| US-20110223177-A1 | TREATMENT OF FIBROTIC EYE DISORDERS | UNIVERSITY OF EAST ANGLIA (GB) | 2011-09-15 | — | — | US | claimed |
| US-20110130388-A1 | PROPHYLACTIC OR THERAPEUTIC AGENT FOR AXIAL MYOPIA | OSAKA UNIVERSITY (JP) | 2011-06-02 | — | — | US | claimed |
| EP-2319539-A1 | PROPHYLACTIC OR THERAPEUTIC AGENT FOR AXIAL MYOPIA | Osaka University (JP) | 2011-05-11 | — | — | EP | claimed |
| US-12618830-B2 | Methods, culture medias and devices for generating embryos in vitro from stem cells | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2026-05-05 | — | — | US | disclosed |
| US-12618049-B2 | Reprogramming methods and cell culture platforms | FATE THERAPEUTICS, INC. (US) | 2026-05-05 | — | — | US | disclosed |
| WO-1998022457-A9 | ARYL AND HETEROARYL SUBSTITUTED FUSED PYRROLE ANTIINFLAMMATORY AGENTS | — | 1998-08-20 | — | — | WO | disclosed |
| WO-1998022457-A1 | ARYL AND HETEROARYL SUBSTITUTED FUSED PYRROLE ANTIINFLAMMATORY AGENTS | AMGEN INC. (US) | 1998-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12618049-B2 | Reprogramming methods and cell culture platforms | WNT3A, FGF2, MEF2D | IMPDH2 1463/4885MAPK1 13/4885HSD17B10 3251/4885 |
| US-20110130388-A1 | PROPHYLACTIC OR THERAPEUTIC AGENT FOR AXIAL MYOPIA | RHOA, ROCK1, ROCK2 | IMPDH2 4145/4885MAPK1 22/4885HSD17B10 2910/4885 |
| US-12618830-B2 | Methods, culture medias and devices for generating embryos in vitro from stem cells | POU2F1, POU5F1, POU2F2 | IMPDH2 3421/4885MAPK1 628/4885HSD17B10 4580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.