SCHEMBL3500701

SCHEMBL3500701

CCN(CC)CCOc1ccccc1NC(=O)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.60
MCHR1 Q99705 5/20 0.57
ALDH1A1 P00352 2/20 0.55
KDM4E B2RXH2 1/20 0.55
LMNA P02545 1/20 0.55
CACNA1H O95180 1/20 0.52
CACNA1B Q00975 1/20 0.52
EBP Q15125 1/20 0.51
SIGMAR1 Q99720 1/20 0.51
PTK2 Q05397 1/20 0.50
P4HTM Q9NXG6 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
HTT P42858 1/20 0.49
HDAC1 Q13547 1/20 0.49
HDAC8 Q9BY41 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49
DRD2 P14416 1/20 0.49
DRD1 P21728 1/20 0.49
DRD3 P35462 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6898504 0.91 GAA (0.56) GAAMCHR1ALDH1A1KDM4ELMNA
SCHEMBL7056986 0.91 CACNA1H (0.63) GAAMCHR1ALDH1A1CACNA1HCACNA1B
SCHEMBL6925417 0.90 GAA (0.58) GAAMCHR1ALDH1A1KDM4ELMNA
SCHEMBL6926348 0.89 GAA (0.57) GAAMCHR1ALDH1A1KDM4ELMNA
SCHEMBL6926037 0.88 TSHR (0.55) GAAMCHR1LMNANPC1RAB9A
SCHEMBL6922557 0.88 KDR (0.50) GAAMCHR1ALDH1A1KDM4ELMNA
SCHEMBL6927791 0.88 GAA (0.59) GAAMCHR1ALDH1A1KDM4ELMNA
SCHEMBL7051105 0.88 MEN1 (0.58) MCHR1CACNA1HCACNA1BNPC1RAB9A
SCHEMBL6927664 0.87 MCHR1 (0.61) GAAMCHR1ALDH1A1KDM4ELMNA
SCHEMBL6928305 0.83 MCHR1 (0.52) GAAMCHR1ALDH1A1CACNA1HCACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160369237-A1 METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY ADVANCED CELL TECH INC (US) 2016-12-22 US disclosed
US-20100184033-A1 METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY Lineage Cell Therapeutics, Inc. 2010-07-22 US disclosed
US-20080226601-A1 Herpes Virus-Based Compositions and Methods of Use in the Prenatal and Perinatal Periods UNIVERSITY OF ROCHESTER (US) 2008-09-18 US disclosed
EP-1903873-A2 HERPES VIRUS-BASED COMPOSITIONS AND METHODS OF USE IN THE PRENATAL AND PERINATAL PERIODS THE UNIVERSITY OF ROCHESTER (US) 2008-04-02 EP disclosed
US-20080070303-A1 Using myocardial and/or muscle progenitor cells as modeling tool in tissue engineering; regenerative medicine and organ replacement ADVANCED CELL TECHNOLOGY 2008-03-20 US disclosed
WO-2007062198-A1 METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY ADVANCED CELL TECHNOLOGY, INC. (US) 2007-05-31 WO disclosed
WO-2006135602-A2 HERPES VIRUS-BASED COMPOSITIONS AND METHODS OF USE IN THE PRENATAL AND PERINATAL PERIODS UNIVERSITY OF ROCHESTER (US) 2006-12-21 WO disclosed