Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 5/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | CFD | P00746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18412824 | 0.86 | PTGDR2 (0.50) | PTGDR2MAPTL3MBTL1POLBLMNA | |
| SCHEMBL1110869 | 0.84 | PTGDR2 (0.51) | PTGDR2MAPTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL17973685 | 0.84 | PTGDR2 (0.51) | PTGDR2MAPTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL89047 | 0.82 | PTGDR2 (0.49) | PTGDR2MAPTL3MBTL1POLBLMNA | |
| SCHEMBL20505374 | 0.81 | TSHR (0.61) | PTGDR2MAPTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL27684806 | 0.79 | PTGDR2 (0.50) | PTGDR2MAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL4763424 | 0.79 | KDM4E (0.58) | MAPTL3MBTL1POLBLMNASMN1; SMN2 | |
| SCHEMBL17957944 | 0.78 | PTGDR2 (0.49) | PTGDR2LMNAKDM4EMAOAMAOB | |
| SCHEMBL1530794 | 0.78 | PTGDR2 (0.77) | PTGDR2L3MBTL1POLBMAOAMAOB | |
| SCHEMBL4207937 | 0.78 | PTGDR2 (0.51) | PTGDR2MAPTLMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | GPR34, GPR4, GPR6 | PTGDR2 249/4885MAPT 4820/4885L3MBTL1 4412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.