Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3498324 | 0.93 | MAPT (0.33) | MAPTNPSR1 | |
| SCHEMBL3501468 | 0.92 | MEN1 (0.31) | MAPTKMT2AMEN1NPSR1TSHR | |
| SCHEMBL3500973 | 0.92 | MEN1 (0.31) | MAPTKMT2AMEN1NPSR1 | |
| SCHEMBL3498993 | 0.91 | MAPT (0.31) | MAPT | |
| SCHEMBL3499830 | 0.86 | L3MBTL1 (0.32) | MAPTNPSR1 | |
| SCHEMBL2661012 | 0.85 | MAPT (0.35) | MAPTKMT2AMEN1NPSR1TSHR | |
| SCHEMBL3499992 | 0.84 | NFKBIA (0.38) | MAPTKMT2AMEN1 | |
| SCHEMBL2978318 | 0.83 | MAPT (0.34) | MAPTKMT2AMEN1NPSR1TSHR | |
| SCHEMBL2661009 | 0.83 | MAPT (0.34) | MAPTKMT2AMEN1NPSR1TSHR | |
| SCHEMBL2668859 | 0.83 | MAPT (0.35) | MAPTKMT2AMEN1NPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410087-B2 | Indole compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-04-02 | — | — | US | disclosed |
| US-20100144702-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144702-A1 | INDOLE COMPOUND | GCKR, GPR119, SLC5A1 | MAPT 4224/4885KMT2A 507/4885MEN1 2138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.