Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TK2 | O00142 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27633872 | 0.87 | TK1 (0.39) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL1583331 | 0.84 | TK1 (0.44) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL15893327 | 0.84 | TK1 (0.44) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL16099482 | 0.84 | TK1 (0.44) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL6025787 | 0.83 | TK1 (0.43) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL6025793 | 0.83 | TK1 (0.43) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL18039264 | 0.83 | TK1 (0.43) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL27437189 | 0.83 | TK1 (0.40) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL292198 | 0.82 | LMNA (0.45) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL4745548 | 0.82 | TK1 (0.43) | TK1LMNASMN1; SMN2TK2ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100183639-A1 | NUCLEIC ACID-LIPOPHILIC CONJUGATES | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2010-07-22 | — | — | US | disclosed |
| US-7615539-B2 | Nucleic acid-lipophilic conjugates | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2009-11-10 | — | — | US | disclosed |
| EP-1730281-A2 | IMMUNOSTIMULATORY NUCLEIC ACIDS FOR INDUCING IL-10 RESPONSES | Coley Pharmaceutical Group, Inc. (US) | 2006-12-13 | — | — | EP | disclosed |
| US-20060019916-A1 | Immunostimulatory nucleic acids for inducing IL-10 responses | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2006-01-26 | — | — | US | disclosed |
| WO-2005111057-A2 | IMMUNOSTIMULATORY NUCLEIC ACIDS FOR INDUCING IL-10 RESPONSES | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2005-11-24 | — | — | WO | disclosed |
| US-20050130911-A1 | Nucleic acid-lipophilic conjugates | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2005-06-16 | — | — | US | disclosed |