Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11363078 | 1.00 | GPR84 (0.48) | GPR84FFAR1FFAR4TSHRSPHK1 | |
| SCHEMBL2818859 | 1.00 | GPR84 (0.48) | GPR84FFAR1FFAR4TSHRSPHK1 | |
| SCHEMBL15153583 | 1.00 | GPR84 (0.48) | GPR84FFAR1FFAR4TSHRSPHK1 | |
| SCHEMBL2818864 | 1.00 | GPR84 (0.48) | GPR84FFAR1FFAR4TSHRSPHK1 | |
| SCHEMBL8402045 | 1.00 | GPR84 (0.48) | GPR84FFAR1FFAR4TSHRSPHK1 | |
| SCHEMBL4977789 | 1.00 | GPR84 (0.48) | GPR84FFAR1FFAR4TSHRSPHK1 | |
| SCHEMBL5480087 | 0.98 | GPR84 (0.45) | GPR84FFAR1FFAR4TSHRSPHK1 | |
| SCHEMBL3501156 | 0.91 | — | — | |
| SCHEMBL15153431 | 0.83 | TSHR (0.54) | GPR84FFAR1FFAR4TSHRSPHK1 | |
| SCHEMBL19039336 | 0.83 | TSHR (0.54) | GPR84FFAR1FFAR4TSHRSPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214825-A1 | Method For Producing Substituted Halopyridines | ARCHIMICA GMBH (DE) | 2008-09-04 | — | — | US | claimed |
| US-7091011-B2 | 3-hydroxycarboxylic acid production and use in branched polymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-08-15 | — | — | US | claimed |
| US-20030170837-A1 | 3-hydroxycarboxylic acid production and use in branched polymers | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2003-09-11 | — | — | US | claimed |
| US-20030166180-A1 | 3-Hydroxycarboxylic acid production and use in branched polymers | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2003-09-04 | — | — | US | claimed |
| EP-1309715-A2 | 3-HYDROXYCARBOXYLIC ACID PRODUCTION AND USE IN BRANCHED POLYMERS | E.I. Dupont de Nemours and Company (US) | 2003-05-14 | — | — | EP | claimed |
| US-6562603-B2 | Forming hydroxy group containing acid from hydroxy groupcontaining nitrile; polylactones | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-05-13 | — | — | US | claimed |
| US-20020039770-A1 | 3-Hydroxycarboxylic acid production and use in branched polymers | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2002-04-04 | — | — | US | claimed |
| WO-2002012530-A2 | 3-HYDROXYCARBOXYLIC ACID PRODUCTION AND USE IN BRANCHED POLYMERS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2002-02-14 | — | — | WO | claimed |
| CN-110416609-B | Non-aqueous electrolyte of lithium ion battery and lithium ion battery comprising same | 珠海市赛纬电子材料股份有限公司 | 2022-02-11 | — | — | CN | disclosed |
| EP-3052101-B1 | SLOW-RELEASE CONJUGATES OF SN-38 | PROLYNX LLC (US) | 2019-11-20 | — | — | EP | disclosed |
| US-20100143989-A1 | Production Of 3-Hydroxycarboxylic Acid Using Nitrilase Mutants | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-10 | — | — | US | disclosed |
| US-20080214825-A1 | Method For Producing Substituted Halopyridines | ARCHIMICA GMBH (DE) | 2008-09-04 | — | — | US | disclosed |
| EP-1778840-B1 | PRODUCTION OF 3-HYDROXYCARBOXYLIC ACID USING NITRILASE MUTANTS | DU PONT (US) | 2008-06-11 | — | — | EP | disclosed |
| US-7358071-B2 | Production of 3-hydroxycarboxylic acid using nitrilase mutants | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-04-15 | — | — | US | disclosed |
| US-6562603-B2 | Forming hydroxy group containing acid from hydroxy groupcontaining nitrile; polylactones | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-05-13 | — | — | US | disclosed |
| US-20020039770-A1 | 3-Hydroxycarboxylic acid production and use in branched polymers | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2002-04-04 | — | — | US | disclosed |
| WO-2002012530-A2 | 3-HYDROXYCARBOXYLIC ACID PRODUCTION AND USE IN BRANCHED POLYMERS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2002-02-14 | — | — | WO | disclosed |
| EP-0611119-B1 | Optically active compound, liquid crystal composition containing same, liquid crystal device, display apparatus and display method | CANON KK (JP) | 1999-06-23 | — | — | EP | disclosed |
| US-5830386-A | FLUOROALKYL-SUBSTITUTED PYRIMIDINE | CANON KABUSHIKI KAISHA (JP) | 1998-11-03 | — | — | US | disclosed |
| EP-0611119-A2 | Optically active compound, liquid crystal composition containing same, liquid crystal device, display apparatus and display method | CANON KABUSHIKI KAISHA (JP) | 1994-08-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100143989-A1 | Production Of 3-Hydroxycarboxylic Acid Using Nitrilase Mutants | CYP2W1, O60361, HAO2 | GPR84 1007/4885FFAR1 91/4885FFAR4 82/4885 |
| US-20080214825-A1 | Method For Producing Substituted Halopyridines | CBR3, HRH4, CBR1 | GPR84 1657/4885FFAR1 1321/4885FFAR4 565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.