SCHEMBL3501491

SCHEMBL3501491

CN(CC(=O)O)C(=O)C(CS)NC(=O)CCC(N)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.59
GSTK1 Q9Y2Q3 1/20 0.59
GLO1 Q04760 1/20 0.49
NOD1 Q9Y239 10/20 0.46
FOLH1 Q04609 2/20 0.41
GRM8 O00222 1/20 0.40
GRM6 O15303 1/20 0.40
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
GSR P00390 1/20 0.40
CYP1A2 P05177 1/20 0.40
GRIK1 P39086 1/20 0.40
GRM5 P41594 1/20 0.40
GRIA1 P42261 1/20 0.40
GRIA2 P42262 1/20 0.40
GRIA3 P42263 1/20 0.40
SLC1A3 P43003 1/20 0.40
SLC1A2 P43004 1/20 0.40
SLC1A1 P43005 1/20 0.40
GRIA4 P48058 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24645944 0.88 NOD1 (0.53) PTGS1GSTK1GLO1NOD1FOLH1
SCHEMBL16057141 0.87 PTGS1 (0.56) PTGS1GSTK1GLO1NOD1FOLH1
SCHEMBL5463061 0.86 PTGS1 (0.61) PTGS1GSTK1GLO1NOD1FOLH1
SCHEMBL1332934 0.86 PTGS1 (0.61) PTGS1GSTK1GLO1NOD1FOLH1
SCHEMBL316091 0.85 PTGS1 (0.60) PTGS1GSTK1GLO1NOD1FOLH1
SCHEMBL19549046 0.85 PTGS1 (0.60) PTGS1GSTK1GLO1NOD1FOLH1
SCHEMBL928710 0.85 PTGS1 (0.59) PTGS1GSTK1GLO1NOD1FOLH1
SCHEMBL1296494 0.85 PTGS1 (0.56) PTGS1GSTK1GLO1NOD1FOLH1
SCHEMBL236404 0.85 PTGS1 (0.56) PTGS1GSTK1GLO1NOD1FOLH1
SCHEMBL8591691 0.85 PTGS1 (0.56) PTGS1GSTK1GLO1NOD1FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1853292-B1 PHARMACEUTICAL COMPOSITION COMPRISING GLUTATHIONE COMPOUNDS AND BETALAIN FOR THE PREVENTION AND TREATMENT OF CANCER GERNOT TREUSCH (ES) 2008-12-10 EP claimed
WO-2025054048-A1 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING LIPID AND CHOLESTEROL METABOLISM ASSOCIATED DISEASES, DISORDERS, AND CONDITIONS MarvelBiome, Inc. (US) 2025-03-13 WO disclosed
EP-4440342-A1 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING VAGUS NERVE ASSOCIATED DISEASES, DISORDERS, AND CONDITIONS MarvelBiome, Inc. (US) 2024-10-09 EP disclosed
WO-2023102149-A1 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING VAGUS NERVE ASSOCIATED DISEASES, DISORDERS, AND CONDITIONS MarvelBiome, Inc. (US) 2023-06-08 WO disclosed
US-20220208386-A1 DIAGNOSTIC FOR MATERNAL RISK OF HAVING A CHILD WITH AUTISM SPECTRUM DISORDER ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2022-06-30 US disclosed
CN-114008045-A Agrohorticultural agent containing novel imidazopyridine-2-carboxamide derivative as active ingredient 阿格罗-金正株式会社 2022-02-01 CN disclosed
CN-113227373-A Control of coleopteran insects 绿光生物科技股份有限公司 2021-08-06 CN disclosed
US-10231958-B2 Methods and compositions for enhancing chemotherapy THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2019-03-19 US disclosed
WO-2018211450-A1 COMPOSITION AND METHODS FOR INHIBITION OF METAL CORROSION FOR USE IN THE OIL AND GAS INDUSTRY KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2018-11-22 WO disclosed
US-20170326120-A1 METHODS AND COMPOSITIONS FOR ENHANCING CHEMOTHERAPY THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2017-11-16 US disclosed
EP-2398500-A2 GLUTATHIONE-BASED DRUG DELIVERY SYSTEM TO-BBB Holding B.V. (NL) 2011-12-28 EP disclosed
WO-2010095940-A2 GLUTATHIONE-BASED DRUG DELIVERY SYSTEM TO-BBB HOLDING B.V. (NL) 2010-08-26 WO disclosed
US-20100184601-A1 Method and Means Relating to Multiple Herbicide Resistance in Plants UNIVERSITY OF DURHAM (GB) 2010-07-22 US disclosed
EP-1853292-B1 PHARMACEUTICAL COMPOSITION COMPRISING GLUTATHIONE COMPOUNDS AND BETALAIN FOR THE PREVENTION AND TREATMENT OF CANCER GERNOT TREUSCH (ES) 2008-12-10 EP disclosed
EP-1853292-A1 PHARMACEUTICAL COMPOSITION FOR THE PREVENTION AND TREATMENT OF CANCER Gernot, Treusch (ES) 2007-11-14 EP disclosed
WO-2006084768-A1 PHARMACEUTICAL COMPOSITION FOR THE PREVENTION AND TREATMENT OF CANCER GERNOT TREUSCH (ES) 2006-08-17 WO disclosed
US-6242244-B1 Microbial system for formaldehyde sensing and remediation WISCONSIN ALUMNI RESEARCH FOUNDATION 2001-06-05 US disclosed
US-5837481-A DETECTING FORMALDEHYDE IN WASTE SAMPLING, USING A RHODOBACTER SPHAEROIDES BACTERIAL CELL COMPRISING A GENETIC ENGINEERED LINKED GENE ENCODING A PROTEIN ENZYME TO DETECT, GENERATING A SIGNAL, BIOREMEDIATING, DETOXIFICATION WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1998-11-17 US disclosed
US-5834300-A DETOXIFICATION BY BIOREMEDIATION; DETECTING THE FORMALDEHYDE IN A SAMPLE BY A PROTEIN, OXIDIZING THE FORMALDEHYDE BY DEHYDROGENASE PROTEIN, BOTH PROTEINS ARE CODED FROM A GENETIC ENGINEERED GENE WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1998-11-10 US disclosed
US-5747328-A GENETIC ENGINEERING WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1998-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100184601-A1 Method and Means Relating to Multiple Herbicide Resistance in Plants GSTO1, GSTP1, GSR PTGS1 830/4885GSTK1 9/4885GLO1 29/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.