SCHEMBL3501786

SCHEMBL3501786

CCCCCCCCCCCCCC(CC)OCCOCCOCCOCCOCCO

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
THRB P10828 1/20 0.58
HTT P42858 1/20 0.58
MAPT P10636 1/20 0.58
TSHR P16473 1/20 0.48
LMNA P02545 3/20 0.41
USP2 O75604 2/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPK1 P28482 1/20 0.41
CASP1 P29466 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
SLCO1B3 Q9NPD5 1/20 0.41
SLCO1B1 Q9Y6L6 1/20 0.41
DNM1 Q05193 1/20 0.38
LPAR1 Q92633 4/20 0.36
LPAR3 Q9UBY5 4/20 0.36
LPAR2 Q9HBW0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29521479 1.00 MEN1 (0.58) MEN1KMT2ATHRBHTTMAPT
SCHEMBL2369348 0.98 MEN1 (0.55) MEN1KMT2ATHRBHTTMAPT
SCHEMBL2369313 0.98 MEN1 (0.55) MEN1KMT2ATHRBHTTMAPT
SCHEMBL24266 0.98 MEN1 (0.55) MEN1KMT2ATHRBHTTMAPT
SCHEMBL25363941 0.93 TSHR (0.52) MEN1KMT2ATHRBHTTMAPT
SCHEMBL31601754 0.93 TSHR (0.52) MEN1KMT2ATHRBHTTMAPT
SCHEMBL3362082 0.93 TSHR (0.52) MEN1KMT2ATHRBHTTMAPT
SCHEMBL5146487 0.93 MEN1 (0.62) MEN1KMT2ATHRBHTTMAPT
SCHEMBL1628205 0.93 MEN1 (0.62) MEN1KMT2ATHRBHTTMAPT
SCHEMBL1626655 0.93 MEN1 (0.62) MEN1KMT2ATHRBHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2514406-A1 Spontaneously dispersible preconcentrates including a peptide drug in a solid or semisolid carrier Novo Nordisk A/S (DK) 2012-10-24 EP disclosed
EP-2497462-A1 Stable non-aqueous pharmaceutical compositions Novo Nordisk A/S (DK) 2012-09-12 EP disclosed
US-20100190706-A1 Stable Non-Aqueous Pharmaceutical Compositions NOVO NORDISK A/S (DK) 2010-07-29 US disclosed
EP-2164466-A1 SPONTANEOUSLY DISPERSIBLE PRECONCENTRATES INCLUDING A PEPTIDE DRUG IN A SOLID OR SEMISOLID CARRIER Novo Nordisk A/S (DK) 2010-03-24 EP disclosed
EP-2164459-A1 STABLE NON-AQUEOUS PHARMACEUTICAL COMPOSITIONS Novo Nordisk A/S (DK) 2010-03-24 EP disclosed
WO-2008145732-A1 STABLE NON-AQUEOUS PHARMACEUTICAL COMPOSITIONS NOVO NORDISK A/S (DK) 2008-12-04 WO disclosed
WO-2008145728-A1 SPONTANEOUSLY DISPERSIBLE PRECONCENTRATES INCLUDING A PEPTIDE DRUG IN A SOLID OR SEMISOLID CARRIER NOVO NORDISK A/S (DK) 2008-12-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100190706-A1 Stable Non-Aqueous Pharmaceutical Compositions IAPP, NONO, GPR119 MEN1 1062/4885KMT2A 4672/4885THRB 1473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.