SCHEMBL35018

SCHEMBL35018

CCC(C)C1=Nc2ccccc2C1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 1/20 0.36
TSHR P16473 1/20 0.36
NOS3 P29474 1/20 0.35
NOS1 P29475 1/20 0.35
NOS2 P35228 1/20 0.35
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.35
ALDH1A1 P00352 2/20 0.35
MAPT P10636 2/20 0.35
KDM4E B2RXH2 1/20 0.35
PKM P14618 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TRPA1 O75762 3/20 0.34
SIGMAR1 Q99720 1/20 0.34
HTR2A P28223 3/20 0.34
HRH1 P35367 2/20 0.34
HPGD P15428 1/20 0.31
DPP8 Q6V1X1 2/20 0.30
DPP9 Q86TI2 2/20 0.30
DPP7 Q9UHL4 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1101901 0.81 HRH4 (0.40) HRH4NOS3NOS1NOS2NPC1
SCHEMBL16383317 0.78 HRH4 (0.38) HRH4NOS3NOS1NOS2NPC1
SCHEMBL16383318 0.73 NOS3 (0.39) HRH4NOS3NOS1NOS2NPC1
SCHEMBL822111 0.69 HRH4 (0.40) HRH4NOS3NOS1NOS2NPC1
SCHEMBL13408650 0.69 HRH4 (0.37) HRH4NOS3NOS1NOS2NPC1
SCHEMBL22085098 0.69 HRH4 (0.33) HRH4NOS3NOS1NOS2NPC1
SCHEMBL13816110 0.68 NOS3 (0.52) HRH4NOS3NOS1NOS2NPC1
SCHEMBL24181419 0.66 MAPT (0.40) HRH4NPC1RAB9AALDH1A1MAPT
SCHEMBL47849 0.66 NOS3 (0.43) HRH4TSHRNOS3NOS1NOS2
SCHEMBL10983250 0.66 HRH4 (0.44) HRH4TSHRNOS3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020116971-A1 COMPOUNDS HAVING PDE9A INHIBITORY ACTIVITY, AND PHARMACEUTICAL USES THEREOF 한국화학연구원 2020-06-11 WO disclosed
US-9997791-B2 Membrane electrode units for high temperature fuel cells with improved stability BASF SE (DE) 2018-06-12 US disclosed
US-20180123155-A1 PROTON-CONDUCTING MEMBRANE, METHOD FOR THEIR PRODUCTION AND THEIR USE IN ELECTROCHEMICAL CELLS BASF SE (DE) 2018-05-03 US disclosed
US-9825320-B2 Process for the manufacture of membrane electrode units BASF SE (DE) 2017-11-21 US disclosed
US-9812725-B2 Proton-conducting membrane and use thereof BASF SE (DE) 2017-11-07 US disclosed
US-9680156-B2 Composition, polymer thereof, electrode and electrolyte membrane for fuel cell, and fuel cell including the same SAMSUNG ELECTRONICS CO., LTD (KR) 2017-06-13 US disclosed
US-9559367-B2 Long-life membrane electrode assemblies and its use in fuel cells BASF FUEL CELL GMBH (DE) 2017-01-31 US disclosed
US-9537166-B2 Method for the production of an electrochemical cell RENSSELAER POLYTECHNIC INSTITUTE (US) 2017-01-03 US disclosed
US-9515341-B2 Porous membrane, electrolyte membrane including same, methods of manufacturing both, and fuel cell including at least one of the membranes SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-12-06 US disclosed
US-9484588-B2 Compound, composition including compound, composite formed therefrom, electrode using composition or composite, composite membrane using composite, and fuel cell including at least one selected from electrode and composite membrane SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-11-01 US disclosed
US-20080026277-A1 For polymer electrolyte membranes (PEM) fuel cells; polyazole film with smooth and rough side, doped with acid; e.g. polybenzimidazoles, polypyridobisimidazoles, polyareneazoles; good mechanical properties and an excellence proton conductivity; use with reformates from hydrocarbons BASF FUEL CELL GMBH (DE) 2008-01-31 US disclosed
US-20070292734-A1 Polymer electrolyte membrane, method for the production thereof, and application thereof in fuel cells BASF FUEL CELL GMBH (DE) 2007-12-20 US disclosed
US-20070281204-A1 Membrane Electrode Assemblies and Highly Durable Fuel Cells PEMEAS GMBH (DE) 2007-12-06 US disclosed
US-20070248889-A1 Membrane Electrode Units and Fuel Cells with an Increased Service Life PEMEAS GMBH (DE) 2007-10-25 US disclosed
US-20070248863-A1 Membrane-Electrode Unit and Fuel Elements with Increased Service Life BASF FUEL CELL GMBH (DE) 2007-10-25 US disclosed
US-20070202415-A1 Proton-Conducting Polymer Membrane Comprising At Least One Porous Carrier Material, And Use Thereof In Fuel Cells PEMEAS GMBH (DE) 2007-08-30 US disclosed
US-20070203252-A1 Anisotropic Shaped Bodies, Method For The Production And Utilization Of Anisotropic Shaped Bodies PEMEAS GMBH (DE) 2007-08-30 US disclosed
US-7244811-B2 Method for the treatment of polyazole films PEMEAS GMBH (DE) 2007-07-17 US disclosed
US-7235320-B2 Proton-conducting membrane and use thereof PEMEAS GMBH (DE) 2007-06-26 US disclosed
US-20070055045-A1 Proton-conducting polymer membrane containing polymers with sulfonic acid groups that are covalently bonded to aromatic groups, membrane electrode unit, and use thereof in fuel cells PEMEAS GMBH (DE) 2007-03-08 US disclosed