SCHEMBL3501931

SCHEMBL3501931

NCCCCCC[CH]C(N)=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
LMNA P02545 3/20 0.42
THRB P10828 2/20 0.42
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
PLG P00747 1/20 0.42
ALOX15 P16050 1/20 0.42
SLC6A2 P23975 1/20 0.42
RECQL P46063 1/20 0.42
SLC6A3 Q01959 1/20 0.42
PAOX Q6QHF9 3/20 0.41
BLM P54132 3/20 0.40
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA3 P07451 2/20 0.40
CA4 P22748 2/20 0.40
CA6 P23280 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1629675 0.97
SCHEMBL1630881 0.90
SCHEMBL27282392 0.80 LMNA (0.48) MAOAMAOBLMNATHRBKMT2A
SCHEMBL27291286 0.80 LMNA (0.48) MAOAMAOBLMNATHRBKMT2A
SCHEMBL1632473 0.78
SCHEMBL16458602 0.78 FAAH (0.57) LMNAKMT2AMEN1ALOX15SLC6A2
SCHEMBL7146817 0.78 FAAH (0.57) LMNAKMT2AMEN1ALOX15SLC6A2
SCHEMBL11322157 0.78 FAAH (0.57) LMNAKMT2AMEN1ALOX15SLC6A2
SCHEMBL10656809 0.78 FAAH (0.57) LMNAKMT2AMEN1ALOX15SLC6A2
SCHEMBL19124847 0.78 PAOX (0.50) MAOAMAOBLMNATHRBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2021488-B1 USE OF BASE-MODIFIED DEOXYNUCLEOSIDE TRIPHOSPHATES TO IMPROVE NUCLEIC ACID DETECTION KUTYAVIN IGOR (US) 2018-09-12 EP disclosed
US-8349556-B2 Use of base-modified deoxynucleoside triphosphates to improve nucleic acid detection KUTYAVIN IGOR (US) 2013-01-08 US disclosed
US-20100151455-A1 USE OF BASE-MODIFIED DEOXYNUCLEOSIDE TRIPHOSPHATES TO IMPROVE NUCLEIC ACID DETECTION KUTYAVIN IGOR 2010-06-17 US disclosed
EP-2021488-A2 USE OF BASE-MODIFIED DEOXYNUCLEOSIDE TRIPHOSPHATES TO IMPROVE NUCLEIC ACID DETECTION Kutyavin, Igor (US) 2009-02-11 EP disclosed
WO-2007127992-A2 USE OF BASE-MODIFIED DEOXYNUCLEOSIDE TRIPHOSPHATES KUTYAVIN IGOR (US) 2007-11-08 WO disclosed
EP-1140967-A1 TARGETED GENE TRANSFER USING G PROTEIN COUPLED RECEPTORS UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2001-10-10 EP disclosed
WO-2000039145-A1 TARGETED GENE TRANSFER USING G PROTEIN COUPLED RECEPTORS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2000-07-06 WO disclosed