SCHEMBL350324

SCHEMBL350324

CCNS(=O)(=O)c1cccc(C)c1

nearest known ligand 0.77

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.77
ALDH1A1 P00352 2/20 0.62
KAT6A Q92794 1/20 0.54
MEN1 O00255 1/20 0.53
FBP1 P09467 11/20 0.53
AKR1C3 P42330 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31404044 1.00 KMT2A (0.77) KMT2AALDH1A1KAT6AMEN1FBP1
SCHEMBL11707958 0.86 KMT2A (0.83) KMT2AALDH1A1KAT6AFBP1AKR1C3
SCHEMBL24956750 0.84 KMT2A (0.74) KMT2AALDH1A1KAT6AMEN1FBP1
SCHEMBL13763465 0.84 KMT2A (0.74) KMT2AALDH1A1KAT6AMEN1FBP1
SCHEMBL8548241 0.83 KMT2A (0.78) KMT2AALDH1A1KAT6AFBP1AKR1C3
SCHEMBL11706540 0.82 KMT2A (0.76) KMT2AALDH1A1FBP1AKR1C3
SCHEMBL17277340 0.81 KMT2A (0.81) KMT2AALDH1A1KAT6AFBP1AKR1C3
SCHEMBL4810591 0.81 KMT2A (0.70) KMT2AALDH1A1KAT6AMEN1FBP1
SCHEMBL13188853 0.81 KMT2A (0.81) KMT2AALDH1A1KAT6AMEN1FBP1
SCHEMBL11704757 0.80 KMT2A (0.73) KMT2AALDH1A1MEN1FBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 536 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024113031-A1 POLYETHYLENE TEREPHTHALATE-BASED ADHESIVE REPAIR PATCH FOR ANTI-CORROSIVE COATINGS, METHOD FOR PRODUCING SAME AND USE THEREOF Petróleo Brasileiro S.A. - Petrobras (BR) 2024-06-06 WO claimed
US-8940105-B2 Sulfonamide-doped undercoat for imaging device XEROX CORPORATION (US) 2015-01-27 US claimed
US-8414695-B2 Thermal ink jet ink composition VIDEOJET TECHNOLOGIES INC. 2013-04-09 US claimed
US-20120225380-A1 Sulfonamide-doped undercoat for imaging device XEROX CORPORATION (US) 2012-09-06 US claimed
US-20120147087-A1 THERMAL INK JET INK COMPOSITION ROBERTSON CASEY (US) 2012-06-14 US claimed
US-8142558-B2 Thermal ink jet ink composition VIDEOJET TECHNOLOGIES INC. 2012-03-27 US claimed
EP-2353582-A1 Cosmetic composition for eyelashes L'Oréal (FR) 2011-08-10 EP claimed
US-20110150805-A1 MAKEUP COMPOSITION L'OREAL (FR) 2011-06-23 US claimed
EP-2158941-A2 Emulsion Nail coating comprising a specific gelling agent L'Oréal (FR) 2010-03-03 EP claimed
US-20090263338-A1 NAIL VARNISH L'OREAL (FR) 2009-10-22 US claimed
EP-0064330-B1 SYNTHETIC RESIN BLENDS FOR PACKAGING FILMS AND METHODS OF PRODUCTION OF SUCH FILMS AMERICAN CAN COMPANY (US) 1986-03-19 EP claimed
US-4552801-A Plasticized EVOH and process and products utilizing same AMERICAN CAN COMPANY (US) 1985-11-12 US claimed
EP-0157426-A2 Flame retardant thermoplastic polyester molding composition E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-10-09 EP claimed
EP-0063006-B1 ETHYLENE VINYL ALCOHOL COPOLYMER BLEND, A PROCESS FOR PRODUCING A COMPOSITE FILM THEREFROM AND THE COMPOSITE FILM PER SE AMERICAN CAN COMPANY (US) 1985-08-28 EP claimed
US-4451599-A Plasticized EVOH and process and products utilizing same AMERICAN CAN COMPANY (US) 1984-05-29 US claimed
EP-0064330-A1 Synthetic resin blends for packaging films and methods of production of such films AMERICAN CAN COMPANY (US) 1982-11-10 EP claimed
EP-0063006-A1 Ethylene vinyl alcohol copolymer blend, a process for producing a composite film therefrom and the composite film per se AMERICAN CAN COMPANY (US) 1982-10-20 EP claimed
US-4347332-A Polyamide/polyethylene copolymer film and method for producing AMERICAN CAN COMPANY (US) 1982-08-31 US claimed
US-4222923-A Adhesive composition and method of use RHODES JOHN 1980-09-16 US claimed
US-4060262-A Record material THE STANDARD REGISTER COMPANY (US) 1977-11-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110150805-A1 MAKEUP COMPOSITION KRT18, CUTA, LAGE3 KMT2A 324/4885ALDH1A1 2340/4885KAT6A 295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.