SCHEMBL3503299

SCHEMBL3503299

NC(=O)C(Cl)(Cl)C(Cl)(Cl)Cl

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
OR51E2 Q9H255 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.33
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1577631 0.74 ALDH1A1 (0.35) ALDH1A1TP53TSHR
SCHEMBL31272081 0.73 F2 (0.31) ALDH1A1TP53TSHR
SCHEMBL116271 0.72
SCHEMBL30995902 0.72 ALDH1A1 (0.50) ALDH1A1LMNAOR51E2TDP1TP53
SCHEMBL17077964 0.69
Hydrochloric Acid SCHEMBL31092070 0.69
Ammonia Solution, Strong SCHEMBL21381330 0.69
SCHEMBL11002111 0.69
SCHEMBL31272238 0.67 ALDH1A1 (0.30) ALDH1A1TP53TSHR
SCHEMBL31272417 0.67 ALDH1A1 (0.30) ALDH1A1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024248021-A1 FILM-FORMING COMPOSITION, METHOD FOR PRODUCING SUBSTRATE, AND METHOD FOR PRODUCING FILM-FORMING COMPOSITION セントラル硝子株式会社 2024-12-05 WO disclosed
US-20220096643-A1 Acryloyloxyethylphosphorylcholine Containing Polymer Conjugates And Their Preparation KODIAK SCIENCES INC (US) 2022-03-31 US disclosed
EP-1988910-B1 ACRYLOYLOXYETHYLPHOSPHORYLCHOLINE CONTAINING POLYMER CONJUGATES AND THEIR PREPARATION KODIAK SCIENCES INC (US) 2017-12-06 EP disclosed
EP-3222142-A1 ACRYLOYLOXYETHYLPHOSPHORYLCHOLINE CONTAINING POLYMER CONJUGATES AND THEIR PREPARATION Kodiak Sciences Inc. (US) 2017-09-27 EP disclosed
US-20150050714-A1 Acryloyloxyethylphosphorylcholine Containing Polymer Conjugates And Their Preparation OLIGASIS, LLC (US) 2015-02-19 US disclosed
US-8846021-B2 Acryloyloxyethylphosphorylcholine containing polymer conjugates and their preparation OLIGASIS, LLC (US) 2014-09-30 US disclosed
US-20130337534-A1 Acryloyloxyethylphosphorylcholine Containing Polymer Conjugates And Their Preparation OLIGASIS, LLC (US) 2013-12-19 US disclosed
US-20100166700-A1 Acryloyloxyethylphosphorylcholine Containing Polymer Conjugates and Their Preparation OLIGASIS CORPORATION (US) 2010-07-01 US disclosed
EP-1988910-A2 ACRYLOYLOXYETHYLPHOSPHORYLCHOLINE CONTAINING POLYMER CONJUGATES AND THEIR PREPARATION Oligasis Corporation (US) 2008-11-12 EP disclosed
WO-2007100905-A2 ACRYLOYLOXYETHYLPHOSPHORYLCHOLINE CONTAINING POLYMER CONJUGATES AND THEIR PREPARATION NEXGEN THERAPEUTICS, LLC (US) 2007-09-07 WO disclosed
WO-2007100902-A2 ACRYLOYLOXYETHYLPHOSPHORYLCHOLINE CONTAINING POLYMER CONJUGATES AND THEIR PREPARATION OLIGASIS CORPORATION (US) 2007-09-07 WO disclosed
CN-1053672-C Azasteroid compounds for the treatment of prostatic hypertrophy SANKYO CO (JP) 2000-06-21 CN disclosed
CN-1062145-A Azasteroid compounds for the treatment of prostatic hypertrophy, their preparation and use SANKYO CO (JP) 1992-06-24 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100166700-A1 Acryloyloxyethylphosphorylcholine Containing Polymer Conjugates and Their Preparation PHOSPHO1, PCTP, SGMS1 ALDH1A1 2399/4885LMNA 1276/4885OR51E2 3592/4885
US-20220096643-A1 Acryloyloxyethylphosphorylcholine Containing Polymer Conjugates And Their Preparation PHOSPHO1, PCTP, SGMS1 ALDH1A1 2399/4885LMNA 1276/4885OR51E2 3592/4885
US-20130337534-A1 Acryloyloxyethylphosphorylcholine Containing Polymer Conjugates And Their Preparation PHOSPHO1, PCTP, SGMS1 ALDH1A1 2399/4885LMNA 1276/4885OR51E2 3592/4885
US-20150050714-A1 Acryloyloxyethylphosphorylcholine Containing Polymer Conjugates And Their Preparation PHOSPHO1, PCTP, SGMS1 ALDH1A1 2399/4885LMNA 1276/4885OR51E2 3592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.