⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27843000 | 0.92 | KDM4E (0.31) | — | |
| SCHEMBL8453266 | 0.82 | ALDH1A1 (0.38) | — | |
| SCHEMBL3219463 | 0.77 | — | — | |
| SCHEMBL328971 | 0.74 | TSHR (0.39) | — | |
| SCHEMBL8882005 | 0.73 | — | — | |
| SCHEMBL351061 | 0.73 | — | — | |
| SCHEMBL16955460 | 0.73 | — | — | |
| SCHEMBL2649838 | 0.73 | KDM4E (0.31) | — | |
| SCHEMBL351330 | 0.73 | — | — | |
| SCHEMBL979388 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 361 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117903140-A | Imidazopyrimidines and triazolopyrimidines as A2A/A2B inhibitors | 因赛特公司 | 2024-04-19 | — | — | CN | claimed |
| CN-117024430-A | Bipyrimidine fluorene compound, organic electroluminescent element and consumer product | 浙江八亿时空先进材料有限公司 | 2023-11-10 | — | — | CN | claimed |
| CN-109476668-B | 6, 7-dihydro-4H-pyrazolo [1,5-a ] pyrazines and 6, 7-dihydro-4H-triazolo [1,5-a ] pyrazines for the treatment of infectious diseases | 豪夫迈·罗氏有限公司 | 2022-03-22 | — | — | CN | claimed |
| EP-3897644-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | Revolution Medicines, Inc. (US) | 2021-10-27 | — | — | EP | claimed |
| CN-113498342-A | Compounds involved in synergistic binding and uses thereof | 锐新医药公司 | 2021-10-12 | — | — | CN | claimed |
| EP-3759112-A1 | IMIDAZOPYRIMIDINES AND TRIAZOLOPYRIMIDINES AS A2A / A2B INHIBITORS | Incyte Corporation (US) | 2021-01-06 | — | — | EP | claimed |
| US-10781206-B2 | Tetrahydropyrazolopyridine compounds for the treatment of infectious diseases | HOFFMANN LA-ROCHE INC. (US) | 2020-09-22 | — | — | US | claimed |
| WO-2020132597-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | Revolution Medicines, Inc. (US) | 2020-06-25 | — | — | WO | claimed |
| US-20200197391-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | Revolution Medicines, Inc. | 2020-06-25 | — | — | US | claimed |
| US-10683299-B2 | Pyrazolopyrazine and triazolopyrazine compounds for the treatment of infectious diseases | HOFFMANN LA ROCHE INC. (US) | 2020-06-16 | — | — | US | claimed |
| WO-2003006464-A1 | (1,8) NAPHTHYRIDINES AS GABA LIGANDS, THEIR PHARMACEUTICAL COMPOSITIONS AND USES | MERCK SHARP & DOHME LIMITED (GB) | 2003-01-23 | — | — | WO | claimed |
| US-20020161224-A1 | Diaryl ethers and processes for their preparation and herbicidal and desiccant compositions containing them | PULMAN DAVID A (US) | 2002-10-31 | — | — | US | claimed |
| WO-2002076983-A1 | IMIDAZO-PYRIMIDINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LIMITED (GB) | 2002-10-03 | — | — | WO | claimed |
| US-6333296-B1 | FOR CONTRILLING WEEDS | ISK AMERICAS INCORPORATED | 2001-12-25 | — | — | US | claimed |
| EP-0973395-A4 | DIARYL ETHERS AND PROCESSES FOR THEIR PREPARATION AND HERBICIDAL AND DESICCANT COMPOSITIONS CONTAINING THEM | ISK AMERICAS INC (US) | 2001-10-04 | — | — | EP | claimed |
| EP-0973395-A1 | DIARYL ETHERS AND PROCESSES FOR THEIR PREPARATION AND HERBICIDAL AND DESICCANT COMPOSITIONS CONTAINING THEM | ISK Americas Incorporated (US) | 2000-01-26 | — | — | EP | claimed |
| WO-1998041093-A1 | DIARYL ETHERS AND PROCESSES FOR THEIR PREPARATION AND HERBICIDAL AND DESICCANT COMPOSITIONS CONTAINING THEM | ISK AMERICAS INCORPORATED (US) | 1998-09-24 | — | — | WO | claimed |
| EP-0375404-B1 | Heterocyclic derivatives | ICI PLC (GB) | 1994-02-09 | — | — | EP | claimed |
| US-5098930-A | Inhibitors of lipoxygenase for treatment of diseases mediated with leukotrienes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-24 | — | — | US | claimed |
| EP-0375404-A2 | Heterocyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-27 | — | — | EP | claimed |