Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | GLA | P06280 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12774648 | 0.75 | ALDH1A1 (0.68) | POLBALDH1A1GLAKMT2AMEN1 | |
| SCHEMBL4111126 | 0.72 | ALDH1A1 (0.63) | POLBALDH1A1GLAKMT2AMEN1 | |
| SCHEMBL3138057 | 0.72 | ALDH1A1 (0.63) | POLBALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL761217 | 0.72 | ALDH1A1 (0.63) | POLBALDH1A1GLAKMT2AMEN1 | |
| SCHEMBL15308195 | 0.71 | ALDH1A1 (1.00) | POLBALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL23016797 | 0.70 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL21976700 | 0.69 | CYP1A2 (0.69) | POLBALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL14229106 | 0.69 | TSHR (0.85) | ALDH1A1GLATSHRKMT2AMEN1 | |
| SCHEMBL15882764 | 0.68 | ALDH1A1 (0.71) | POLBALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10455037 | 0.68 | MCOLN3 (0.54) | ALDH1A1TSHRLMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184601-A1 | Method and Means Relating to Multiple Herbicide Resistance in Plants | UNIVERSITY OF DURHAM (GB) | 2010-07-22 | — | — | US | claimed |
| EP-2190290-A2 | METHOD AND MEANS RELATING TO MULTIPLE HERBICIDE RESISTANCE IN PLANTS | University Of Durham (GB) | 2010-06-02 | — | — | EP | claimed |
| WO-2009034396-A2 | METHOD AND MEANS RELATING TO MULTIPLE HERBICIDE RESISTANCE IN PLANTS | UNIVERSITY OF DURHAM (GB) | 2009-03-19 | — | — | WO | claimed |
| US-20100184601-A1 | Method and Means Relating to Multiple Herbicide Resistance in Plants | UNIVERSITY OF DURHAM (GB) | 2010-07-22 | — | — | US | disclosed |
| US-20100184601-A1 | Method and Means Relating to Multiple Herbicide Resistance in Plants | UNIVERSITY OF DURHAM (GB) | 2010-07-22 | — | — | US | disclosed |
| EP-2190290-A2 | METHOD AND MEANS RELATING TO MULTIPLE HERBICIDE RESISTANCE IN PLANTS | University Of Durham (GB) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009034396-A2 | METHOD AND MEANS RELATING TO MULTIPLE HERBICIDE RESISTANCE IN PLANTS | UNIVERSITY OF DURHAM (GB) | 2009-03-19 | — | — | WO | disclosed |
| WO-2009034396-A2 | METHOD AND MEANS RELATING TO MULTIPLE HERBICIDE RESISTANCE IN PLANTS | UNIVERSITY OF DURHAM (GB) | 2009-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184601-A1 | Method and Means Relating to Multiple Herbicide Resistance in Plants | GSTO1, GSTP1, GSR | POLB 2753/4885ALDH1A1 431/4885GLA 1046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.