Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL67163 | 0.78 | CYP2B6 (0.55) | CYP2B6MEN1KMT2A | |
| Cycloheptane SCHEMBL27301709 | 0.75 | — | — | |
| Alcohol SCHEMBL27591126 | 0.71 | — | — | |
| SCHEMBL19983 | 0.71 | TRPA1 (0.31) | — | |
| SCHEMBL29901519 | 0.71 | TRPA1 (0.31) | — | |
| Hydrogen Sulfide SCHEMBL27732874 | 0.69 | TRPA1 (0.31) | — | |
| SCHEMBL27543379 | 0.69 | TRPA1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7403491 | 0.69 | TRPA1 (0.31) | — | |
| SCHEMBL433359 | 0.69 | TRPA1 (0.31) | — | |
| Ammonia Solution, Strong SCHEMBL27596721 | 0.69 | TRPA1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100196355-A1 | Immunophilin Ligands and Methods for Modulating Immunophilin and Calcium Channel Activity | WYETH (US) | 2010-08-05 | — | — | US | disclosed |
| EP-2077853-A1 | IMMUNOPHILIN LIGANDS AND METHODS FOR MODULATING IMMUNOPHILIN AND CALCIUM CHANNEL ACTIVITY | Wyeth (US) | 2009-07-15 | — | — | EP | disclosed |
| WO-2008094147-A1 | IMMUNOPHILIN LIGANDS AND METHODS FOR MODULATING IMMUNOPHILIN AND CALCIUM CHANNEL ACTIVITY | WYETH (US) | 2008-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100196355-A1 | Immunophilin Ligands and Methods for Modulating Immunophilin and Calcium Channel Activity | CACNG4, CACNG7, CACNG2 | CYP2B6 4868/4885MEN1 3776/4885KMT2A 4596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.