Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.68 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.68 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.68 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.66 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.66 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.66 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.66 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.66 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.66 |
| ▸ | LDHA | P00338 | 1/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.66 |
| ▸ | FBP1 | P09467 | 1/20 | 0.66 |
| ▸ | SRC | P12931 | 1/20 | 0.66 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.66 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.66 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.66 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.66 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30208039 | 0.89 | CA1 (0.73) | ADORA1ADORA3ADORA2AADORA2BP2RY1 | |
| SCHEMBL2294876 | 0.89 | CA1 (0.73) | ADORA1ADORA3ADORA2AADORA2BP2RY1 | |
| SCHEMBL14201601 | 0.89 | CA1 (0.73) | ADORA1ADORA3ADORA2AADORA2BP2RY1 | |
| SCHEMBL2294870 | 0.89 | CA1 (0.73) | ADORA1ADORA3ADORA2AADORA2BP2RY1 | |
| SCHEMBL1066377 | 0.88 | TAS1R3 (0.75) | ADORA1ADORA3ADORA2AADORA2BP2RY1 | |
| SCHEMBL29754360 | 0.88 | TAS1R3 (0.75) | ADORA1ADORA3ADORA2AADORA2BP2RY1 | |
| SCHEMBL8954219 | 0.88 | TAS1R3 (0.75) | ADORA1ADORA3ADORA2AADORA2BP2RY1 | |
| SCHEMBL11459665 | 0.87 | ADORA1 (0.71) | ADORA1ADORA3ADORA2AADORA2BP2RY1 | |
| SCHEMBL7067739 | 0.85 | ADORA1 (0.71) | ADORA1ADORA3ADORA2AADORA2BP2RY1 | |
| SCHEMBL16554813 | 0.85 | ADORA1 (0.71) | ADORA1ADORA3ADORA2AADORA2BP2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230309833-A1 | METHODS AND MATERIALS FOR USING [18F]-F-ARAG IN CARDIAC IMAGING | CELLSIGHT TECHNOLOGIES INC. (US) | 2023-10-05 | — | — | US | disclosed |
| EP-4188453-A1 | METHODS AND MATERIALS FOR USING [18F]-F-ARAG IN CARDIAC IMAGING | Cellsight Technologies Inc. (US) | 2023-06-07 | — | — | EP | disclosed |
| WO-2022026533-A1 | METHODS AND MATERIALS FOR USING [18F]-F-ARAG IN CARDIAC IMAGING | CELLSIGHT TECHNOLOGIES INC. (US) | 2022-02-03 | — | — | WO | disclosed |
| US-20210187133-A1 | Compounds and Methods of Making Compounds | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2021-06-24 | — | — | US | disclosed |
| US-20150118157-A1 | Compounds and Methods of Making Compounds | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2015-04-30 | — | — | US | disclosed |
| US-9011817-B2 | Compounds and methods of making compounds | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2015-04-21 | — | — | US | disclosed |
| US-20110059014-A1 | COMPOUNDS AND METHODS OF MAKING COMPOUNDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150118157-A1 | Compounds and Methods of Making Compounds | MCL1, TOP2B, TOP1 | ADORA1 1307/4885ADORA3 1555/4885ADORA2A 743/4885 |
| US-20210187133-A1 | Compounds and Methods of Making Compounds | MCL1, TOP1, TOP2B | ADORA1 1493/4885ADORA3 1731/4885ADORA2A 994/4885 |
| US-20110059014-A1 | COMPOUNDS AND METHODS OF MAKING COMPOUNDS | MCL1, TOP2B, TOP1 | ADORA1 1307/4885ADORA3 1555/4885ADORA2A 743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.