Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.48 |
| ▸ | ALB | P02768 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.48 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | POLG | P54098 | 2/20 | 0.43 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.41 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL19555528 | 0.99 | POLB (0.49) | POLBPDE3ALMNACACNA1FALB | |
| SCHEMBL3759571 | 0.84 | POLB (0.55) | POLBPDE3ALMNACACNA1FALB | |
| SCHEMBL4257977 | 0.81 | POLB (0.56) | POLBPDE3ALMNACACNA1FALB | |
| SCHEMBL3485775 | 0.80 | POLB (0.52) | POLBPDE3ALMNACACNA1FALB | |
| SCHEMBL6917219 | 0.80 | POLB (0.53) | POLBPDE3ALMNACACNA1FALB | |
| SCHEMBL6917215 | 0.80 | POLB (0.53) | POLBPDE3ALMNACACNA1FALB | |
| SCHEMBL4254628 | 0.79 | POLG (0.57) | POLBPDE3ALMNACACNA1FALB | |
| SCHEMBL6534196 | 0.79 | POLB (0.47) | POLBPDE3ALMNACACNA1FALB | |
| SCHEMBL992808 | 0.79 | POLB (0.48) | POLBPDE3ALMNACACNA1FALB | |
| SCHEMBL12077056 | 0.79 | POLB (0.48) | POLBPDE3ALMNACACNA1FALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 542 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117157318-A | anti-HVEM antibodies | 免疫治疗有限公司 | 2023-12-01 | — | — | CN | claimed |
| EP-4271712-A1 | ANTI-HVEM ANTIBODIES | Immunomic Therapeutics, Inc. (US) | 2023-11-08 | — | — | EP | claimed |
| WO-2022147108-A1 | ANTI-HVEM ANTIBODIES | IMMUNOMIC THERAPEUTICS, INC. (US) | 2022-07-07 | — | — | WO | claimed |
| EP-3980023-A1 | LIPID NANOPARTICLES CONTAINING PHARMACEUTICAL AND/OR NUTRACEUTICAL AGENTS AND METHODS THEREOF | Board of Regents, The University of Texas System (US) | 2022-04-13 | — | — | EP | claimed |
| EP-3915549-A1 | SENESCENCE INDUCERS FOR USE IN THE TREATMENT AND/OR PREVENTION OF VIRUS INDUCED DISEASES | Merck Patent GmbH (DE) | 2021-12-01 | — | — | EP | claimed |
| US-20210309740-A1 | BISPECIFIC CHIMERIC ANTIGEN RECEPTORS AND THERAPEUTIC USES THEREOF | SEATTLE CHILDREN'S HOSPITAL D/B/A SEATTLE CHILDREN'S RESEARCH INSTITUTE (US) | 2021-10-07 | — | — | US | claimed |
| EP-3615037-A1 | TRIAZOLE BISPHOSPHONATE GERANYLGERANYL DIPHOSPHATE SYNTHASE INHIBITORS | Board of Regents of the University of Nebraska (US) | 2020-03-04 | — | — | EP | claimed |
| US-10189903-B2 | Bispecific chimeric antigen receptors and methods of use thereof to treat cancer | SEATTLE CHILDREN'S HOSPITAL (US) | 2019-01-29 | — | — | US | claimed |
| WO-2018200603-A1 | TRIAZOLE BISPHOSPHONATE GERANYLGERANYL DIPHOSPHATE SYNTHASE INHIBITORS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2018-11-01 | — | — | WO | claimed |
| US-20170107285-A1 | BISPECIFIC CHIMERIC ANTIGEN RECEPTORS AND ENCODING POLYNUCLEOTIDES THEREOF | SEATTLE CHILDREN'S HOSPITAL D/B/A SEATTLE CHILDREN'S RESEARCH INSTITUTE (US) | 2017-04-20 | — | — | US | claimed |
| WO-2005097086-A2 | USE OF 5,10-METHYLENE TETRAHYDROFOLATE FOR THE TREATMENT OF CANCER | ADVENTRX PHARMACEUTICALS, INC. (US) | 2005-10-20 | — | — | WO | claimed |
| US-20050034178-A1 | Stress-responsive induction of a therapeutic agent and methods of use | UNIVERSITY OF SOUTHERN CALIFORNIA | 2005-02-10 | — | — | US | claimed |
| WO-2004111090-A2 | MOLECULES FOR TARGETING AND RELEASING THERAPEUTIC COMPOUNDS, AND THE USE THEREOF | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2004-12-23 | — | — | WO | claimed |
| EP-1351946-A2 | MATERIALS AND METHODS TO POTENTIATE CANCER TREATMENT | ICOS CORPORATION (US) | 2003-10-15 | — | — | EP | claimed |
| WO-2001000791-A9 | STRESS-RESPONSIVE INDUCTION OF A THERAPEUTIC AGENT AND METHODS OF USE | UNIV SOUTHERN CALIFORNIA (US) | 2002-07-25 | — | — | WO | claimed |
| EP-1194527-A1 | STRESS-RESPONSIVE INDUCTION OF A THERAPEUTIC AGENT AND METHODS OF USE | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2002-04-10 | — | — | EP | claimed |
| WO-2002020500-A2 | MATERIALS AND METHODS TO POTENTIATE CANCER TREATMENT | ICOS CORPORATION (US) | 2002-03-14 | — | — | WO | claimed |
| WO-2001000791-A1 | STRESS-RESPONSIVE INDUCTION OF A THERAPEUTIC AGENT AND METHODS OF USE | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2001-01-04 | — | — | WO | claimed |
| EP-0828508-A2 | COMPOSITIONS OF INTERLEUKIN AND PYRIMIDINE NUCLEOSIDES | F. HOFFMANN-LA ROCHE AG (CH) | 1998-03-18 | — | — | EP | claimed |
| WO-1996037214-A2 | COMPOSITIONS OF INTERLEUKIN AND PYRIMIDINE NUCLEOSIDES | F. HOFFMANN-LA ROCHE AG (CH) | 1996-11-28 | — | — | WO | claimed |