Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | POLG | P54098 | 3/20 | 0.54 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.47 |
| ▸ | P2RY4 | P51582 | 4/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.41 |
| ▸ | NT5E | P21589 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.38 |
| ▸ | POLA1 | P09884 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4254628 | 0.98 | POLG (0.57) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL3759571 | 0.92 | POLB (0.55) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL350551 | 0.81 | POLB (0.50) | POLBPOLGP2RY2P2RY4P2RY6 | |
| Hydrochloric Acid SCHEMBL19555528 | 0.80 | POLB (0.49) | POLBPOLGP2RY2P2RY4P2RY6 | |
| Doxecitine SCHEMBL6066348 | 0.79 | POLB (0.69) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL18784964 | 0.78 | POLB (0.80) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL158325 | 0.78 | POLB (0.80) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL158324 | 0.78 | POLB (0.80) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL2220813 | 0.78 | POLB (0.80) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL12595480 | 0.78 | POLB (0.80) | POLBPOLGP2RY2P2RY4P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113573736-B | Modified micrornas and their use in the treatment of cancer | 纽约州州立大学研究基金会 | 2025-03-25 | — | — | CN | disclosed |
| CN-110785187-B | Antibody molecules against CD73 and uses thereof | 诺华股份有限公司 | 2024-04-05 | — | — | CN | disclosed |
| US-20230132256-A1 | COMBINATION THERAPY | OWL ROCK OPPORTUNISTIC MASTER FUND I, L.P. | 2023-04-27 | — | — | US | disclosed |
| WO-2022248268-A1 | COMBINATION THERAPY | ADC THERAPEUTICS SA (CH) | 2022-12-01 | — | — | WO | disclosed |
| CN-113573736-A | Modified microRNAs and their use in the treatment of cancer | 纽约州州立大学研究基金会 | 2021-10-29 | — | — | CN | disclosed |
| EP-3820478-A1 | COMBINATION THERAPY | ADC Therapeutics SA (CH) | 2021-05-19 | — | — | EP | disclosed |
| CN-112367999-A | Combination therapy | ADC治疗有限公司 | 2021-02-12 | — | — | CN | disclosed |
| WO-2020011724-A1 | COMBINATION THERAPY | ADC THERAPEUTICS SA (CH) | 2020-01-16 | — | — | WO | disclosed |
| US-20160058793-A1 | Tumor Targeted Sickle Erythroid Precursors, Progenitors and Hematopoietic Stem Cells, Induced Pluripotent Stem Cells, Microparticles and Liposomes for Treatment of Cancer | TERMAN DAVID S (US) | 2016-03-03 | — | — | US | disclosed |
| US-8388966-B2 | Combination treatment of pancreatic cancer | CANCER ADVANCES, INC. (US) | 2013-03-05 | — | — | US | disclosed |
| US-20090004200-A1 | Combination treatment of pancreatic cancer | CANCER ADVANCES, INC. | 2009-01-01 | — | — | US | disclosed |
| US-20060140962-A1 | Combination treatment of pancreatic cancer | CANCER ADVANCES, INC. | 2006-06-29 | — | — | US | disclosed |
| EP-1372717-A2 | COMBINATION TREATMENT OF PANCREATIC CANCER | APHTON CORPORATION (US) | 2004-01-02 | — | — | EP | disclosed |
| US-20030091574-A1 | Combination treatment of pancreatic cancer | CANCER ADVANCES, INC. | 2003-05-15 | — | — | US | disclosed |
| WO-2002076499-A2 | COMBINATION TREATMENT OF PANCREATIC CANCER | APHTON CORPORATION (US) | 2002-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230132256-A1 | COMBINATION THERAPY | IL2RA, IL2, CD22 | POLB 3212/4885POLG 1925/4885P2RY2 1253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.