Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | SNCA | P37840 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3506563 | 0.83 | GRM2 (0.38) | — | |
| SCHEMBL3506560 | 0.83 | GRM2 (0.38) | — | |
| SCHEMBL3505525 | 0.82 | LIPG (0.35) | CLK1MEN1KMT2A | |
| SCHEMBL3505103 | 0.80 | DRD2 (0.34) | MEN1KMT2A | |
| SCHEMBL3504925 | 0.80 | DRD2 (0.34) | MEN1KMT2A | |
| SCHEMBL3505662 | 0.80 | DRD2 (0.34) | MEN1KMT2A | |
| SCHEMBL3505070 | 0.80 | DRD2 (0.34) | MEN1KMT2A | |
| SCHEMBL3506627 | 0.80 | DRD2 (0.34) | MEN1KMT2A | |
| SCHEMBL3503416 | 0.80 | DRD2 (0.34) | MEN1KMT2A | |
| SCHEMBL3505527 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5475014-A | Monoamine oxidase inhibor; antidepressant | EISAI CO., LTD. (JP) | 1995-12-12 | — | — | US | claimed |
| US-20100247543-A1 | TREATMENT AND PREVENTION OF NEURODEGENERATIVE DISEASES | ORYZON GENOMICS, S.A. (ES) | 2010-09-30 | — | — | US | disclosed |