SCHEMBL350704

SCHEMBL350704

NC(C(=O)O)C(C(=O)O)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.53
SLC1A2 P43004 7/20 0.43
SLC1A1 P43005 7/20 0.43
SLC1A3 P43003 6/20 0.43
USP2 O75604 1/20 0.40
SLCO1B1 Q9Y6L6 1/20 0.40
PTGS1 P23219 2/20 0.36
SLC7A11 Q9UPY5 1/20 0.36
GRM2 Q14416 1/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL350703 1.00 SLC7A5 (0.53) SLC7A5SLC1A2SLC1A1SLC1A3USP2
Bicarbonate SCHEMBL12986986 0.97 SLC7A5 (0.50) SLC7A5SLC1A2SLC1A1SLC1A3USP2
SCHEMBL29524472 0.82 SLC7A5 (0.57) SLC7A5SLC1A2SLC1A1SLC1A3USP2
SCHEMBL5284864 0.82 SLC7A5 (0.57) SLC7A5SLC1A2SLC1A1SLC1A3USP2
SCHEMBL1007447 0.81 SLC7A5 (0.62) SLC7A5SLC1A2SLC1A1SLC1A3USP2
SCHEMBL25933046 0.81 SLC7A5 (0.62) SLC7A5SLC1A2SLC1A1SLC1A3USP2
SCHEMBL468084 0.81 SLC7A5 (0.62) SLC7A5SLC1A2SLC1A1SLC1A3USP2
SCHEMBL600021 0.81 SLC7A5 (0.62) SLC7A5SLC1A2SLC1A1SLC1A3USP2
SCHEMBL29957453 0.81 SLC7A5 (0.62) SLC7A5SLC1A2SLC1A1SLC1A3USP2
SCHEMBL28302170 0.78 SLC7A5 (0.40) SLC7A5SLC1A2SLC1A1SLC1A3USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4262880-A1 PEPTIDE-LINKED DRUG DELIVERY SYSTEM Cornell University (US) 2023-10-25 EP claimed
WO-2022140289-A1 PEPTIDE-LINKED DRUG DELIVERY SYSTEM CORNELL UNIVERSITY (US) 2022-06-30 WO claimed
EP-1542939-A1 OLIGOMERIC DISPERSANT Construction Research & Technology GmbH (DE) 2005-06-22 EP claimed
US-6861459-B2 Making a dry cast article with hydraulic cement, water, coarse particles and a polymeric flow control agents CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2005-03-01 US claimed
US-6713511-B1 TREATING NEUROTRANSMITTER OR NERVOUS SYSTEM DEFECTS OR DEFICIENCIES; ACYLATED DERIVATIVES OF TYROSINE, LEVODOPA AND DOPAMINE YEHUDA ZVI (IL) 2004-03-30 US claimed
WO-2004024647-A1 OLIGOMERIC DISPERSANT CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2004-03-25 WO claimed
EP-1373189-A4 FATTY ACID DERIVATIVES YEHUDA ZVI (IL) 2004-01-02 EP claimed
EP-1373189-A1 FATTY ACID DERIVATIVES Yehuda, Zvi (IL) 2004-01-02 EP claimed
US-20030181579-A1 Oligomeric dispersant CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2003-09-25 US claimed
EP-0785793-B1 ALLOSTERIC MODULATORS OF THE NMDA RECEPTOR BEARSDEN BIO INC (US) 2003-07-30 EP claimed
US-6511963-B1 Treating excitotoxicity resulting from over- stimulation of the NMDA receptor which comprises administering agent selected from the group consisting of Conantokin-G, a Conantokin-G derivative and salts thereof BEARSDEN BIO, INC. 2003-01-28 US claimed
US-6451881-B1 Oligomeric dispersant MBT HOLDINGAG (CH) 2002-09-17 US claimed
US-6284731-B1 POLYPEPTIDES BEARSDEN BIO, INC. 2001-09-04 US claimed
US-6133347-A CEMENT AND A DISPERSANT COMPRISING THE REACTION PRODUCT OF A WATER SOLUBLE NONIONIC POLYMER NONADSORBING TO CEMENT PARTICLES, SUCH AS POLYOXYALKYLENE GLYCOLS, AND SPECIFIED FUNCTIONAL MOIETY THAT ADSORB ONTO A PARTICLE MBT HOLDING AG (CH) 2000-10-17 US claimed
EP-0785793-A4 ALLOSTERIC MODULATORS OF THE NMDA RECEPTOR BEARSDEN BIO INC (US) 2000-08-30 EP claimed
WO-2000009476-B1 FATTY ACID DERIVATIVES YEHUDA ZVI (IL) 2000-04-27 WO claimed
WO-2000009476-A1 FATTY ACID DERIVATIVES YEHUDA ZVI (IL) 2000-02-24 WO claimed
US-5658885-A OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1997-08-19 US claimed
EP-0785793-A1 ALLOSTERIC MODULATORS OF THE NMDA RECEPTOR Bearsden Bio, Inc. (US) 1997-07-30 EP claimed
WO-1996011698-A1 ALLOSTERIC MODULATORS OF THE NMDA RECEPTOR SYMPHONY PHARMACEUTICALS, INC. (US) 1996-04-25 WO claimed