Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.41 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.40 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3509597 | 0.95 | SMN1; SMN2 (0.48) | SMN1; SMN2HTTLMNASLC1A1CA1 | |
| SCHEMBL3506453 | 0.93 | SMN1; SMN2 (0.49) | SMN1; SMN2HTTLMNASLC1A1CA1 | |
| SCHEMBL4769824 | 0.82 | SMN1; SMN2 (0.67) | SMN1; SMN2HTTLMNAALDH1A1L3MBTL1 | |
| SCHEMBL3510726 | 0.78 | CA1 (0.50) | HTTSLC1A1CA1CA2CA7 | |
| SCHEMBL19839625 | 0.78 | TLR2 (0.57) | PLA2G10PLA2G2A | |
| SCHEMBL25876429 | 0.78 | FOLH1 (0.49) | SMN1; SMN2HTTSLC1A1CA1CA2 | |
| SCHEMBL3510751 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2HTTLMNASLC1A1ALDH1A1 | |
| SCHEMBL3508948 | 0.77 | SMN1; SMN2 (0.62) | SMN1; SMN2HTTLMNAALDH1A1L3MBTL1 | |
| SCHEMBL31078034 | 0.76 | SLC1A1 (0.49) | SLC1A1CA1CA2CA7CA9 | |
| SCHEMBL21070867 | 0.76 | SMN1; SMN2 (0.60) | SMN1; SMN2HTTLMNAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234351-A1 | FUSED NITROGEN-COMPRISING HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234351-A1 | FUSED NITROGEN-COMPRISING HETEROCYCLIC COMPOUND | NR0B2, NR0B1, NR4A3 | SMN1; SMN2 974/4885HTT 2877/4885LMNA 2664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.