Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 2/20 | 0.44 |
| ▸ | PAM | P19021 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6139421 | 0.92 | SLC1A1 (0.48) | SLC1A1CA1CA2CA7CA9 | |
| SCHEMBL9716343 | 0.86 | PLA2G10 (0.48) | — | |
| SCHEMBL17277090 | 0.84 | HTT (0.46) | SLC1A1CA1CA2CA7CA9 | |
| SCHEMBL22661236 | 0.84 | CA1 (0.46) | SLC1A1CA1CA2CA7CA9 | |
| SCHEMBL28610357 | 0.82 | ALDH1A1 (0.46) | SLC1A1CA1CA2CA7CA9 | |
| SCHEMBL4535810 | 0.81 | TSHR (0.58) | SLC1A1CA1CA2CA7CA9 | |
| SCHEMBL25876429 | 0.81 | FOLH1 (0.49) | SLC1A1CA1CA2CA7CA9 | |
| SCHEMBL23447236 | 0.80 | ALDH1A1 (0.54) | CA1CA2CA9PAMMAPK1 | |
| SCHEMBL9575541 | 0.80 | TSHR (0.56) | SLC1A1CA1CA2CA7CA9 | |
| SCHEMBL231282 | 0.79 | TSHR (0.61) | TSHRPAMMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240287105-A1 | TREPROSTINIL ANALOGS AND RELATED METHODS OF MAKING AND USING | UNITED THERAPEUTICS CORPORATION (US) | 2024-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240287105-A1 | TREPROSTINIL ANALOGS AND RELATED METHODS OF MAKING AND USING | TYMP, TTPA, PTGIS | SLC1A1 2233/4885CA1 4237/4885CA2 4775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.