Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 4/20 | 0.48 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3511989 | 0.88 | TYMP (0.44) | TYMPTYMS | |
| SCHEMBL3511991 | 0.88 | TYMP (0.44) | TYMPTYMS | |
| SCHEMBL262080 | 0.88 | TYMP (0.51) | TYMPTYMSDNMT1POLBADRB1 | |
| SCHEMBL6391314 | 0.88 | TYMP (0.51) | TYMPTYMSDNMT1POLBADRB1 | |
| SCHEMBL17747092 | 0.87 | TYMP (0.51) | TYMPTYMSDNMT1POLBADRB1 | |
| SCHEMBL3510678 | 0.87 | TYMP (0.43) | TYMPTYMSPOLB | |
| SCHEMBL3510681 | 0.87 | TYMP (0.43) | TYMPTYMSPOLB | |
| SCHEMBL26647607 | 0.84 | TYMS (0.53) | TYMPTYMS | |
| SCHEMBL26647537 | 0.84 | TYMS (0.53) | TYMPTYMS | |
| SCHEMBL6885492 | 0.83 | POLB (0.53) | TYMPTYMSDNMT1POLBADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100290992-A1 | NANOPARTICLE NUCLEIC ACID BINDING COMPOUND CONJUGATES FORMING I-MOTIFS | ROCHE DIAGNOSTICS GMBH (DE) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100290992-A1 | NANOPARTICLE NUCLEIC ACID BINDING COMPOUND CONJUGATES FORMING I-MOTIFS | POLM, IGF2BP1, POLRMT | TYMP 479/4885TYMS 785/4885DNMT1 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.