Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014737 | 0.69 | ALDH1A1 (0.41) | HPGDHSD17B10TDP1ALDH1A1MAPT | |
| SCHEMBL5585123 | 0.69 | PTGS1 (0.46) | ALDH1A1MAPTPTGS1SLC7A11 | |
| SCHEMBL28661351 | 0.69 | HPGD (0.40) | HPGDHSD17B10TDP1ALDH1A1MAPT | |
| SCHEMBL300184 | 0.67 | — | — | |
| SCHEMBL9273466 | 0.67 | ALDH1A1 (0.45) | HPGDHSD17B10TDP1ALDH1A1MAPT | |
| SCHEMBL14603511 | 0.66 | ODC1 (0.36) | TDP1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL4325459 | 0.65 | — | — | |
| SCHEMBL11386829 | 0.65 | — | — | |
| SCHEMBL7613000 | 0.65 | CYP1A2 (0.43) | ALDH1A1MAPTMEN1KMT2APTGS1 | |
| SCHEMBL22980744 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120329176-A1 | INDIRECTLY LABELLED ASSAY CONJUGATES AND METHODS OF PREPARING AND USING SAME | ABBOTT LABORATORIES (US) | 2012-12-27 | — | — | US | disclosed |
| US-20100279432-A1 | INDIRECTLY LABELLED ASSAY CONJUGATES AND METHODS OF PREPARING AND USING SAME | ABBOTT LABORATORIES (US) | 2010-11-04 | — | — | US | disclosed |
| US-20090068635-A1 | INDIRECTLY LABELLED ASSAY CONJUGATES AND METHODS OF PREPARING AND USING SAME | ABBOTT LABORATORIES | 2009-03-12 | — | — | US | disclosed |