Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glutamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.68 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.57 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.57 |
| ▸ | GSR | P00390 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | GRM8 | O00222 | 2/20 | 0.53 |
| ▸ | GRM6 | O15303 | 2/20 | 0.53 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.53 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.53 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.53 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.53 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.53 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutamine SCHEMBL6931889 | 1.00 | ALOX15 (0.68) | ALOX15BLMPMP22KMT2APTGS1 | |
| Glutamine SCHEMBL2129419 | 0.93 | ALOX15 (0.79) | ALOX15BLMPMP22KMT2APTGS1 | |
| Glutamine SCHEMBL285915 | 0.93 | ALOX15 (0.79) | ALOX15BLMPMP22KMT2APTGS1 | |
| Glutamine SCHEMBL285916 | 0.93 | ALOX15 (0.79) | ALOX15BLMPMP22KMT2APTGS1 | |
| Glutamine SCHEMBL27338522 | 0.91 | ALOX15 (0.70) | ALOX15BLMPMP22KMT2APTGS1 | |
| Glutamine SCHEMBL2765120 | 0.91 | ALOX15 (0.83) | ALOX15BLMPMP22KMT2AGSR | |
| Glutamine SCHEMBL2765188 | 0.91 | ALOX15 (0.83) | ALOX15BLMPMP22KMT2AGSR | |
| Glutamine SCHEMBL9754277 | 0.91 | ALOX15 (0.83) | ALOX15BLMPMP22KMT2AGSR | |
| Glutamine SCHEMBL869882 | 0.91 | ALOX15 (0.83) | ALOX15BLMPMP22KMT2AGSR | |
| Glutamine SCHEMBL9716082 | 0.91 | ALOX15 (0.83) | ALOX15BLMPMP22KMT2AGSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126229-A | No background contamination | FUJI PHOTO FILM CO., LTD. (JP) | 1992-06-30 | — | — | US | claimed |
| US-8703217-B2 | Methods for rapid production and usage of biogenerated flavors | KRAFT FOODS GROUP BRANDS LLC (US) | 2014-04-22 | — | — | US | disclosed |
| US-7858291-B2 | imagewise exposure, protective layer comprises water-soluble polyvinyl alcohol; phosphonium salts | FUJIFILM CORPORATION (JP) | 2010-12-28 | — | — | US | disclosed |
| US-7556833-B2 | Cheese flavoring systems prepared with bacteriocins | KRAFT FOODS GLOBAL BRANDS LLC (US) | 2009-07-07 | — | — | US | disclosed |
| CN-101273770-A | Method for rapid production and usage of biogenerated flavors | KRAFT FOODS HOLDINGS INC (US) | 2008-10-01 | — | — | CN | disclosed |
| US-7375246-B2 | Sulfhydral containing compounds and methods of using the same | REGENESIS BIOREMEDIATION PRODUCTS INC. (US) | 2008-05-20 | — | — | US | disclosed |
| US-20070231429-A1 | Methods for rapid production and usage of biogenerated flavors | KRAFT FOODS GROUP BRANDS LLC | 2007-10-04 | — | — | US | disclosed |
| EP-1839490-A1 | Method for rapid production and usage of biogenerated flavors | Kraft Foods Holdings, Inc. (US) | 2007-10-03 | — | — | EP | disclosed |
| EP-1186244-B1 | Natural biogenerated cheese flavoring system | KRAFT FOODS HOLDINGS INC (US) | 2005-08-17 | — | — | EP | disclosed |
| US-20050148712-A1 | Polyol esters of sulfhydryl carboxylic acids; treating water and water-containing soils contaminated with metal | FARONE WILLIAM A (US) | 2005-07-07 | — | — | US | disclosed |
| EP-1288722-A2 | Method for preparing lithographic printing plate | FUJI PHOTO FILM CO., LTD. (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-6406724-B1 | MIXTURE OF LACTIC ACID CULTURE OF MILK CONCENTRATES | KRAFT FOODS HOLDINGS, INC. | 2002-06-18 | — | — | US | disclosed |
| EP-1186244-A2 | Natural biogenerated cheese flavoring system | KRAFT FOODS HOLDINGS, INC. (US) | 2002-03-13 | — | — | EP | disclosed |
| US-6174646-B1 | IMAGEWISE HEATING OR EXPOSING IMAGE FORMING MATERIAL TO LASER WHEREIN IMAGE FORMING MATERIAL COMPRISES SUPPORT HAVING RADIATION SENSITIVE LAYER CONTAINING DYE, AN ACID GENERATING COMPOUND CAPABLE OF GENERATING ACID ON IRRADIATION | KONICA CORPORATION (JP) | 2001-01-16 | — | — | US | disclosed |
| US-5994031-A | DEVELOPMENT; WASHING | KONICA CORPORATION (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0911153-A1 | Image forming method | KONICA CORPORATION (JP) | 1999-04-28 | — | — | EP | disclosed |
| US-5149614-A | DEVELOPER COMPOSITIONS FOR PS PLATES AND METHOD FOR DEVELOPING THE SAME WHEREIN THE DEVELOPER COMPOSITION CONTAINS A SURFACTANT HAVING AN ARYL GROUP, AN OXYALKYLENE GROUP AND A SULFATE ESTER OR SULFONIC ACID GROUP | FUJI PHOTO FILM CO., LTD. (JP) | 1992-09-22 | — | — | US | disclosed |
| US-5126229-A | No background contamination | FUJI PHOTO FILM CO., LTD. (JP) | 1992-06-30 | — | — | US | disclosed |
| US-5047309-A | Photosensitive diazonium recording material with sulfur compound containing undercoat layer | FUJI PHOTO FILM CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0415422-A2 | Method for forming images | FUJI PHOTO FILM CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |