SCHEMBL351369

SCHEMBL351369

CN(C)c1ccccc1/C=C/C=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 4/20 0.52
CCND1 P24385 4/20 0.52
ALDH1A1 P00352 6/20 0.43
LMNA P02545 3/20 0.43
MAPK1 P28482 2/20 0.43
TRPA1 O75762 1/20 0.43
ALOX5 P09917 1/20 0.43
CCNB2 O95067 2/20 0.42
CDK1 P06493 2/20 0.42
CCNB1 P14635 2/20 0.42
CCNB3 Q8WWL7 2/20 0.42
GSK3B P49841 1/20 0.41
MAPT P10636 6/20 0.39
GAA P10253 3/20 0.39
TSHR P16473 2/20 0.39
TP53 P04637 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TDP1 Q9NUW8 2/20 0.39
NSD2 O96028 1/20 0.39
EGFR P00533 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5950036 1.00 CDK4 (0.52) CDK4CCND1ALDH1A1LMNAMAPK1
SCHEMBL8650163 0.94 CDK4 (0.46) CDK4CCND1ALDH1A1LMNAMAPK1
SCHEMBL29523356 0.83 GSK3B (0.44) ALDH1A1LMNAMAPK1TRPA1GSK3B
SCHEMBL5950193 0.81 CDK4 (0.48) CDK4CCND1ALDH1A1LMNAMAPK1
SCHEMBL629142 0.81 CDK4 (0.48) CDK4CCND1ALDH1A1LMNAMAPK1
SCHEMBL27964094 0.80 GSK3B (0.38) CDK4CCND1ALDH1A1LMNAMAPK1
SCHEMBL97297 0.79 LMNA (0.55) ALDH1A1LMNAMAPK1GSK3BMAPT
SCHEMBL29954357 0.79 LMNA (0.55) ALDH1A1LMNAMAPK1GSK3BMAPT
SCHEMBL11070320 0.78 CDK4 (0.70) CDK4CCND1ALDH1A1LMNAMAPK1
SCHEMBL16476616 0.78 CDK4 (0.70) CDK4CCND1ALDH1A1LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 304 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120081752-A Trichalcone derivative and preparation method and application thereof 忻州师范学院 2025-06-03 CN claimed
CN-109870417-B Colorimetric gel for rapidly detecting non-standard explosive raw material urea and preparation method thereof 中国科学院新疆理化技术研究所 2021-07-02 CN claimed
CN-109180527-B Organogel compound of p-dimethylamino cinnamaldehyde derivative, preparation method, organogel and application 信阳师范学院 2021-06-01 CN claimed
WO-2019213740-A1 NOVEL DOWNHOLE METHODS AND COMPOSITIONS USED IN SUCH FLUID ENERGY GROUP LTD. (CA) 2019-11-14 WO claimed
CN-109991218-A A kind of preparation method of coagulase Test paper 迪瑞医疗科技股份有限公司 2019-07-09 CN claimed
CN-109870417-A A kind of comparator gel and preparation method thereof quickly detecting non-standard explosion raw material urea 中国科学院新疆理化技术研究所 2019-06-11 CN claimed
CN-109180527-A The organogel compound and preparation method, organogel and application of a kind of pair of dimethylaminocinnamaldehyde derivative 信阳师范学院 2019-01-11 CN claimed
CN-106222674-B A kind of compound hydrochloric acid pickling corrosion inhibitor of melon ring class 贵州大学 2018-12-07 CN claimed
WO-2018222750-A1 INTEGRATED DEVICES FOR RAPID DETECTION OF BENZODIAZEPINES OR OTHER DRUGS IN SOLUTION KNONAP LLC (US) 2018-12-06 WO claimed
CN-104189140-B Photinia serrulata procyanidine as well as preparation method and application thereof 西北农林科技大学 2017-02-15 CN claimed
EP-1844321-A1 TESTING DEVICE System Two Pty Ltd (AU) 2007-10-17 EP claimed
WO-2006107370-A1 TECHNIQUE FOR DETECTING MICROORGANISMS KIMBERLY-CLARK WORLDWIDE, INC. (US) 2006-10-12 WO claimed
US-20060223052-A1 Technique for detecting microorganisms KIMBERLY-CLARK WORLDWIDE, INC. 2006-10-05 US claimed
WO-2006079167-A1 TESTING DEVICE SYSTEM TWO PTY LTD (AU) 2006-08-03 WO claimed
US-20060084176-A1 Detection of uronium salts YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2006-04-20 US claimed
EP-0954560-A1 METHOD AND MEDIUM FOR DETECTING VANCOMYCIN-RESISTANT ENTEROCOCCUS IDEXX LABORATORIES, INC. (US) 1999-11-10 EP claimed
US-5821074-A ANALYZING FOR LEAD ABBOTT LABORATORIES (US) 1998-10-13 US claimed
WO-1998004674-A1 METHOD AND MEDIUM FOR DETECTING VANCOMYCIN-RESISTANT $i(ENTEROCOCCUS) IDEXX LABORATORIES, INC. (US) 1998-02-05 WO claimed
US-5552297-A ANALYZING FOR LEAD IN BODY FLUIDS, BLOOD, REACTION OF AMINOLEVULINIC ACID TO FORM PORPHOBILINOGEN, COLORIMETRIC ABBOTT LABORATORIES (US) 1996-09-03 US claimed
WO-1995021264-A1 TEST KITS AND METHODS FOR EVALUATING STERILIZATION CYCLES ENVIROCON INTERNATIONAL INCORPORATED (US) 1995-08-10 WO claimed