Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 5/20 | 0.70 |
| ▸ | CCND1 | P24385 | 5/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.53 |
| ▸ | CDK1 | P06493 | 3/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.53 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16476616 | 1.00 | CDK4 (0.70) | CDK4CCND1ALDH1A1LMNATRPA1 | |
| SCHEMBL289313 | 0.92 | LMNA (0.65) | CDK4CCND1ALDH1A1LMNATRPA1 | |
| Ammonia Solution, Strong SCHEMBL11527287 | 0.90 | LMNA (0.62) | CDK4CCND1ALDH1A1LMNATRPA1 | |
| SCHEMBL30518886 | 0.86 | TRPA1 (0.71) | CDK4CCND1ALDH1A1LMNATRPA1 | |
| 2-Hydroxycinnamaldehyde SCHEMBL197452 | 0.83 | CDK4 (1.00) | CDK4CCND1ALDH1A1LMNATRPA1 | |
| SCHEMBL11043876 | 0.83 | CDK4 (0.57) | CDK4CCND1ALDH1A1LMNATRPA1 | |
| 2-Hydroxycinnamaldehyde SCHEMBL691039 | 0.83 | CDK4 (1.00) | CDK4CCND1ALDH1A1LMNATRPA1 | |
| SCHEMBL97837 | 0.83 | CDK4 (0.57) | CDK4CCND1ALDH1A1LMNATRPA1 | |
| SCHEMBL1501162 | 0.83 | CDK4 (0.57) | CDK4CCND1ALDH1A1LMNATRPA1 | |
| SCHEMBL629076 | 0.83 | CDK4 (0.57) | CDK4CCND1ALDH1A1LMNATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58099457-A | — | — | None | — | — | JP | disclosed |
| US-4465684-A | ANTIDIABETIC, ANTILIPEMIC AGENT | BAYER AKTIENGESELLSCHAFT (DE) | 1984-08-14 | — | — | US | disclosed |
| JP-S5899457-A | PHENYLENEBIS(ALPHA-CYANOBUTADIENECARBOXYLIC ACID) OR ITS DERIVATIVE AND ITS PREPARATION | TEIJIN LTD | 1983-06-13 | — | — | JP | disclosed |