SCHEMBL3513799

SCHEMBL3513799

NC(Cc1ccc(O)c(F)c1F)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.59
USP2 O75604 3/20 0.59
HIF1A Q16665 3/20 0.59
ALOX15 P16050 3/20 0.59
HSD17B10 Q99714 3/20 0.59
LMNA P02545 3/20 0.59
MAPT P10636 3/20 0.59
BLM P54132 3/20 0.59
PMP22 Q01453 3/20 0.59
KMT2A Q03164 3/20 0.59
RECQL P46063 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
PKM P14618 2/20 0.59
MEN1 O00255 2/20 0.59
CYP3A4 P08684 2/20 0.59
NFKB1 P19838 2/20 0.59
ALDH1A1 P00352 2/20 0.59
NPSR1 Q6W5P4 2/20 0.59
RGS12 O14924 1/20 0.59
CYP2C9 P11712 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3513801 1.00 KDM4E (0.59) KDM4EUSP2HIF1AALOX15HSD17B10
SCHEMBL29141538 0.92 KDM4E (0.51) KDM4EUSP2HIF1AALOX15HSD17B10
SCHEMBL27125031 0.88 KDM4E (0.57) KDM4EUSP2HIF1AALOX15HSD17B10
SCHEMBL9952323 0.88 KDM4E (0.57) KDM4EUSP2HIF1AALOX15HSD17B10
SCHEMBL6046185 0.88 KDM4E (0.57) KDM4EUSP2HIF1AALOX15HSD17B10
SCHEMBL16064338 0.86 KDM4E (0.42) KDM4EUSP2HIF1AALOX15HSD17B10
SCHEMBL25471322 0.85 KDM4E (0.54) KDM4EUSP2HIF1AALOX15HSD17B10
SCHEMBL1527383 0.84 USP2 (0.51) KDM4EUSP2HIF1AALOX15HSD17B10
SCHEMBL9847979 0.84 KDM4E (0.53) KDM4EUSP2HIF1AALOX15HSD17B10
SCHEMBL9848000 0.84 KDM4E (0.53) KDM4EUSP2HIF1AALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10381652-B2 Fuel cell electrode having increased oxygen concentration and methods of preparing electrode NISSAN NORTH AMERICA, INC. (US) 2019-08-13 US claimed
US-20180261852-A1 Fuel Cell Electrode Having Increased Oxygen Concentration and Methods of Preparing Electrode NISSAN MOTOR CO., LTD. (JP) 2018-09-13 US claimed
CN-104004723-B 3,5-bis-fluoro tyrosine translation system and application thereof 中国科学院生物物理研究所 2016-08-17 CN claimed
CN-105420203-A Tyrosine analogue translation system and gene-encoded protein photoinduced electron transfer fluorescence sensor protein family INST OF BIOPHYSICS CHINESE ACAD OF SCIENCES 2016-03-23 CN claimed
CN-104004723-A 3,5-difluoro-tyrosine translation system and application thereof INST BIOPHYSICS CN ACAD SCI 2014-08-27 CN claimed
US-20250242053-A1 RECOMBINANT THERAPEUTIC FMR1 CONSTRUCTS AND METHODS OF TREATING FRAGILE X SYNDROME AND RELATED DISORDERS THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) 2025-07-31 US disclosed
US-20250136651-A1 RECOMBINANT OPTIMIZED MECP2 CASSETTES AND METHODS FOR TREATING RETT SYNDROME AND RELATED DISORDERS THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) 2025-05-01 US disclosed
EP-4473121-A1 RECOMBINANT OPTIMIZED MECP2 CASSETTES AND METHODS FOR TREATING RETT SYNDROME AND RELATED DISORDERS The University Court Of The University of Edinburgh (GB) 2024-12-11 EP disclosed
CN-117279889-A Substituted fluorosulfates and uses thereof 深圳湾实验室 2023-12-22 CN disclosed
WO-2023208081-A1 SUBSTITUTED FLUOROSULFATE AND USE THEREOF Shenzhen Bay Laboratory (CN) 2023-11-02 WO disclosed
WO-2023209364-A1 RECOMBINANT THERAPEUTIC FMR1 CONSTRUCTS AND METHODS OF TREATING FRAGILE X SYNDROME AND RELATED DISORDERS THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) 2023-11-02 WO disclosed
WO-2023144565-A1 RECOMBINANT OPTIMIZED MECP2 CASSETTES AND METHODS FOR TREATING RETT SYNDROME AND RELATED DISORDERS THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) 2023-08-03 WO disclosed
US-20130004462-A1 MODIFIED FACTOR VIII AND FACTOR IX GENES AND VECTORS FOR GENE THERAPY AskBio Inc. 2013-01-03 US disclosed
US-8198421-B2 Modified factor VIII and factor IX genes and vectors for gene therapy ASKLEPIOS BIOPHARMACEUTICAL, INC. (US) 2012-06-12 US disclosed
US-20100284971-A1 MODIFIED FACTOR VIII AND FACTOR IX GENES AND VECTORS FOR GENE THERAPY ASKLEPIOS BIOPHARMACEUTICAL, INC. (US) 2010-11-11 US disclosed
CN-101511373-A Modified factor VIII and factor IX genes and vectors for gene therapy ASKLEPIOS BIOPHARMACEUTICAL IN (US) 2009-08-19 CN disclosed
EP-2037892-A2 MODIFIED FACTOR VIII AND FACTOR IX GENES AND VECTORS FOR GENE THERAPY Asklepios Biopharmaceutical, Inc. (US) 2009-03-25 EP disclosed
WO-2007149852-A2 MODIFIED FACTOR VIII AND FACTOR IX GENES AND VECTORS FOR GENE THERAPY ASKLEPIOS BIOPHARMACEUTICAL, INC. (US) 2007-12-27 WO disclosed
US-20070258899-A1 Diagnostic and therapeutic agents KARYON-CTT LTD (FI) 2007-11-08 US disclosed
WO-2007113385-A1 DIAGNOSTIC AND THERAPEUTIC AGENTS KARYON-CTT LTD (FI) 2007-10-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070258899-A1 Diagnostic and therapeutic agents YBX1, MLX, TPX2 KDM4E 2053/4885USP2 3792/4885HIF1A 2482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.