⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15621025 | 0.83 | — | — | |
| SCHEMBL19817118 | 0.81 | GPR84 (0.44) | — | |
| SCHEMBL27900339 | 0.81 | EGLN1 (0.37) | — | |
| SCHEMBL18975252 | 0.79 | GPR84 (0.48) | — | |
| SCHEMBL27900337 | 0.78 | — | — | |
| SCHEMBL5950720 | 0.77 | — | — | |
| SCHEMBL5950718 | 0.77 | — | — | |
| SCHEMBL8384603 | 0.77 | LMNA (0.53) | — | |
| SCHEMBL5635990 | 0.77 | — | — | |
| SCHEMBL415752 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107002101-A | The biosynthesis of 1,3 butanediols | 英威达技术有限责任公司 | 2017-08-01 | — | — | CN | claimed |
| CN-108026214-A | Vinyl isomerase-dehydratase, enol-dehydratase, linalool-dehydratase and/or crotyl alcohol dehydratase, and methods of making and using same | 基因组股份公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-107208118-A | The non-natural microorganism of energy efficiency with raising | 基因组股份公司 | 2017-09-26 | — | — | CN | disclosed |
| CN-107002101-A | The biosynthesis of 1,3 butanediols | 英威达技术有限责任公司 | 2017-08-01 | — | — | CN | disclosed |
| US-20100279947-A1 | Modifications of apoptin | LEADD B.V. (NL) | 2010-11-04 | — | — | US | disclosed |
| US-20080234466-A1 | Delivery method for the tumor-specific apoptosis-inducing activity of apoptin | LEADD B.V. (NL) | 2008-09-25 | — | — | US | disclosed |
| US-7319034-B2 | Tumor-specific phosphorylation of Apoptin for diagnostic purposes and for detecting the presence of cancer cells or cells that are cancer prone; a method to identify a putative cancer inducing agent | LEADD B.V. (NL) | 2008-01-15 | — | — | US | disclosed |
| WO-2003089936-A1 | ABERRANT-SPECIFIC PATHWAYS | LEADD B.V. (NL) | 2003-10-30 | — | — | WO | disclosed |
| US-20030199009-A1 | Modifications of apoptin | LEADD B.V. (NL) | 2003-10-23 | — | — | US | disclosed |
| WO-2002101030-A1 | METHOD F0R THE ISOLATION OF A CLUSTER OF CELLS FROM AN ISOLATED ORGAN | LEADD B.V. (NL) | 2002-12-19 | — | — | WO | disclosed |
| EP-1264879-A1 | Isolation of a cluster of cells from an isolated organ using magnetic particle | Leadd B.V. (NL) | 2002-12-11 | — | — | EP | disclosed |
| US-20020061296-A1 | Delivery method for the tumor specific apoptosis inducing activity of apoptin | LEADD B.V. (NL) | 2002-05-23 | — | — | US | disclosed |
| EP-1188832-A1 | A delivery method for the tumor specific apoptosis inducing activity of apoptin | Leadd B.V. (NL) | 2002-03-20 | — | — | EP | disclosed |
| WO-2002020809-A1 | A DELIVERY METHOD FOR THE TUMOR SPECIFIC APOPTOSIS INDUCING ACTIVITY OF APOPTIN | LEADD B.V. (NL) | 2002-03-14 | — | — | WO | disclosed |
| EP-1186665-A1 | A delivery method for the tumor specific apoptosis inducing activity of apoptin | Leadd B.V. (NL) | 2002-03-13 | — | — | EP | disclosed |