⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetone SCHEMBL27611604 | 0.94 | LMNA (0.75) | — | |
| Acetone SCHEMBL9194969 | 0.94 | — | — | |
| Acetone SCHEMBL77883 | 0.94 | — | — | |
| Acetone SCHEMBL27643319 | 0.89 | — | — | |
| Acetone SCHEMBL28247279 | 0.89 | — | — | |
| Acetone SCHEMBL1653292 | 0.88 | — | — | |
| Acetone SCHEMBL10752883 | 0.88 | — | — | |
| Acetone SCHEMBL98066 | 0.88 | — | — | |
| Acetone SCHEMBL9249276 | 0.88 | LMNA (0.86) | — | |
| Acetone SCHEMBL6753303 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100279947-A1 | Modifications of apoptin | LEADD B.V. (NL) | 2010-11-04 | — | — | US | disclosed |
| US-20080234466-A1 | Delivery method for the tumor-specific apoptosis-inducing activity of apoptin | LEADD B.V. (NL) | 2008-09-25 | — | — | US | disclosed |
| US-7319034-B2 | Tumor-specific phosphorylation of Apoptin for diagnostic purposes and for detecting the presence of cancer cells or cells that are cancer prone; a method to identify a putative cancer inducing agent | LEADD B.V. (NL) | 2008-01-15 | — | — | US | disclosed |
| US-20040137551-A1 | Cervical acid phosphatase - papanicolaou (CAP-PAP) test kit, method and accesories, processes for producing and using the same | MARKOVIC NENAD S (US) | 2004-07-15 | — | — | US | disclosed |
| US-20040106564-A1 | Use of slpi for treating chronic inflammatory intestinal diseases | VIVOTEC BIOMEDICAL TECHNOLOGIES GMBH (DE) | 2004-06-03 | — | — | US | disclosed |
| WO-2003089936-A1 | ABERRANT-SPECIFIC PATHWAYS | LEADD B.V. (NL) | 2003-10-30 | — | — | WO | disclosed |
| US-20030199009-A1 | Modifications of apoptin | LEADD B.V. (NL) | 2003-10-23 | — | — | US | disclosed |
| EP-1353680-A2 | USE OF SLPI FOR TREATING CHRONIC INFLAMMATORY INTESTINAL DISEASES | Vivotec Biomedical Technologies GmbH (DE) | 2003-10-22 | — | — | EP | disclosed |
| WO-2002101030-A1 | METHOD F0R THE ISOLATION OF A CLUSTER OF CELLS FROM AN ISOLATED ORGAN | LEADD B.V. (NL) | 2002-12-19 | — | — | WO | disclosed |
| EP-1264879-A1 | Isolation of a cluster of cells from an isolated organ using magnetic particle | Leadd B.V. (NL) | 2002-12-11 | — | — | EP | disclosed |
| WO-2002056900-A2 | USE OF SLPI FOR TREATING CHRONIC INFLAMMATORY INTESTINAL DISEASES | VIVOTEC BIOMEDICAL TECHNOLOGIES GMBH (DE) | 2002-07-25 | — | — | WO | disclosed |
| US-20020061296-A1 | Delivery method for the tumor specific apoptosis inducing activity of apoptin | LEADD B.V. (NL) | 2002-05-23 | — | — | US | disclosed |
| EP-1188832-A1 | A delivery method for the tumor specific apoptosis inducing activity of apoptin | Leadd B.V. (NL) | 2002-03-20 | — | — | EP | disclosed |
| WO-2002020809-A1 | A DELIVERY METHOD FOR THE TUMOR SPECIFIC APOPTOSIS INDUCING ACTIVITY OF APOPTIN | LEADD B.V. (NL) | 2002-03-14 | — | — | WO | disclosed |
| EP-1186665-A1 | A delivery method for the tumor specific apoptosis inducing activity of apoptin | Leadd B.V. (NL) | 2002-03-13 | — | — | EP | disclosed |