Acetone

Acetone

SCHEMBL9249276

CC(C)=O.CO.CO.CO

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.86
TSHR P16473 3/20 0.56
THPO P40225 1/20 0.56
FFAR3 O14843 1/20 0.56
LCK P06239 1/20 0.56
FYN P06241 1/20 0.56
CA1 P00915 2/20 0.50
BLM P54132 2/20 0.50
PMP22 Q01453 2/20 0.50
ALOX15 P16050 1/20 0.50
ALDH1A1 P00352 5/20 0.42
CA4 P22748 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
KDM4E B2RXH2 1/20 0.42
CA2 P00918 1/20 0.42
PTGS1 P23219 1/20 0.42
MMP12 P39900 1/20 0.42
NFKB1 P19838 1/20 0.39
TRPA1 O75762 1/20 0.39
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL5025419 1.00 LMNA (0.86) LMNATSHRTHPOFFAR3LCK
Acetone SCHEMBL6753303 1.00
Acetone SCHEMBL10752883 1.00
Acetone SCHEMBL1653292 1.00
Acetone SCHEMBL9248978 1.00 LMNA (0.86) LMNATSHRTHPOFFAR3LCK
Acetone SCHEMBL7029361 1.00 LMNA (0.86) LMNATSHRTHPOFFAR3LCK
Acetone SCHEMBL98066 1.00
Acetone SCHEMBL216164 0.94
Acetone SCHEMBL10613241 0.94
Acetone SCHEMBL27350678 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5401815-A Polymer scale preventive agent, polymerization vessel for preventing polymer scale deposition, and process of producing polymer using said vessel SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-03-28 US disclosed