Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 4/20 | 0.61 |
| ▸ | INPPL1 | O15357 | 3/20 | 0.50 |
| ▸ | INPP5A | Q14642 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.45 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.44 |
| ▸ | ABAT | P80404 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11217365 | 0.83 | ALDH1A1 (0.47) | SRCALDH1A1CYP2A6DRD1ALDH1A3 | |
| SCHEMBL329313 | 0.83 | SRC (0.75) | SRCINPPL1INPP5ACA1CA2 | |
| SCHEMBL3516747 | 0.82 | ALDH1A1 (0.54) | SRCALDH1A1CYP2A6DRD1ALDH1A3 | |
| Ammonia Solution, Strong SCHEMBL10714477 | 0.81 | SRC (0.71) | SRCINPPL1INPP5ACA1CA2 | |
| SCHEMBL8676949 | 0.81 | SRC (0.54) | SRCINPPL1INPP5AALDH1A1CA1 | |
| SCHEMBL11217369 | 0.81 | ALDH1A1 (0.48) | SRCALDH1A1CYP2A6DRD1ALDH1A3 | |
| SCHEMBL13858750 | 0.78 | ALDH1A1 (0.56) | ALDH1A1CYP2A6DRD1ALDH1A3ALDH5A1 | |
| SCHEMBL21800987 | 0.78 | ALDH1A1 (0.50) | SRCALDH1A1CYP2A6DRD1ALDH1A3 | |
| SCHEMBL11666095 | 0.78 | SRC (0.50) | SRCINPPL1INPP5AALDH1A1CA1 | |
| SCHEMBL9019350 | 0.78 | SRC (0.67) | SRCINPPL1INPP5ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009068321-A1 | SITE-DIRECTED HIGH THROUGHPUT SCREENING | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2009-06-04 | — | — | WO | claimed |
| CN-111954525-B | Prodrugs of fused bicyclic C5aR antagonists | 凯莫森特里克斯股份有限公司 | 2023-12-26 | — | — | CN | disclosed |
| US-11608336-B2 | Prodrugs of fused-bicyclic C5aR antagonists | CHEMOCENTRYX, INC. (US) | 2023-03-21 | — | — | US | disclosed |
| CN-111876098-B | Amphiphilic ionomer-reinforced healthy environment-friendly hot melt adhesive and preparation and application thereof | 广东泰强化工实业有限公司 | 2021-10-22 | — | — | CN | disclosed |
| EP-3523297-B1 | NOVEL FURAZAN-3-CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN TREATMENT OF CANCER | UNIV BERLIN FREIE (DE) | 2021-07-07 | — | — | EP | disclosed |
| US-20210052612-A1 | PRODRUGS OF FUSED-BICYCLIC C5aR ANTAGONISTS | CHEMOCENTRYX, INC. | 2021-02-25 | — | — | US | disclosed |
| EP-3773563-A1 | PRODRUGS OF FUSED-BICYCLIC C5AR ANTAGONISTS | ChemoCentryx, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |
| CN-111954525-A | Prodrugs of fused bicyclic C5aR antagonists | 凯莫森特里克斯股份有限公司 | 2020-11-17 | — | — | CN | disclosed |
| CN-111876098-A | Amphiphilic ionomer-reinforced healthy environment-friendly hot melt adhesive and preparation and application thereof | 广东泰强化工实业有限公司 | 2020-11-03 | — | — | CN | disclosed |
| US-10683286-B2 | Furazan-3-carboxylic acid derivatives and use thereof in treatment of cancer | FREIE UNIVERSITAET BERLIN (DE) | 2020-06-16 | — | — | US | disclosed |
| EP-2001886-A2 | PYRROLOTRIAZINE ANILINE PRODRUG COMPOUNDS USEFUL AS KINASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2008-12-17 | — | — | EP | disclosed |
| EP-1641807-B1 | AROMATIC COMPOUNDS AS ALDOLASE INHIBITORS | UNIV TOULOUSE (FR) | 2008-06-18 | — | — | EP | disclosed |
| WO-2008020813-A1 | METHOD OF ELECTRICALLY DETECTING A BIOLOGICAL ANALYTE MOLECULE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2008-02-21 | — | — | WO | disclosed |
| WO-2007103839-A2 | PYRROLOTRIAZINE ANILINE PRODRUG COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-09-13 | — | — | WO | disclosed |
| US-20070213300-A1 | PYRROLOTRIAZINE ANILINE PRODRUG COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2007-09-13 | — | — | US | disclosed |
| US-20070043002-A1 | Aldolase-inhibiting aromatic compounds | UNIVERSITE PAUL SABATIER TOULOUSE III (FR) | 2007-02-22 | — | — | US | disclosed |
| EP-1641807-A2 | AROMATIC COMPOUNDS AS ALDOLASE INHIBITORS | UNIVERSITE PAUL SABATIER TOULOUSE III (FR) | 2006-04-05 | — | — | EP | disclosed |
| WO-2005012313-A2 | ALDOLASE-INHIBITING AROMATIC COMPOUNDS | UNIVERSITE PAUL SABATIER TOULOUSE III (FR) | 2005-02-10 | — | — | WO | disclosed |
| EP-0487343-B1 | Process for preparing a lithographic plate | FUJI PHOTO FILM CO LTD (JP) | 1999-04-28 | — | — | EP | disclosed |
| EP-0487343-A1 | Process for preparing a lithographic plate | Fuji Photo Film Co., Ltd. (JP) | 1992-05-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11608336-B2 | Prodrugs of fused-bicyclic C5aR antagonists | C5AR2, C5AR1, C3AR1 | SRC 1948/4885INPPL1 538/4885INPP5A 462/4885 |
| US-20070043002-A1 | Aldolase-inhibiting aromatic compounds | ALDOA, DERA, AKR1B1 | SRC 3453/4885INPPL1 1864/4885INPP5A 1813/4885 |
| US-20210052612-A1 | PRODRUGS OF FUSED-BICYCLIC C5aR ANTAGONISTS | C5AR2, C5AR1, C3AR1 | SRC 1948/4885INPPL1 538/4885INPP5A 462/4885 |
| US-20070213300-A1 | PYRROLOTRIAZINE ANILINE PRODRUG COMPOUNDS USEFUL AS KINASE INHIBITORS | CDK2, CDK3, CDK1 | SRC 299/4885INPPL1 736/4885INPP5A 1329/4885 |
| US-10683286-B2 | Furazan-3-carboxylic acid derivatives and use thereof in treatment of cancer | FLT3, MCL1, MYD88 | SRC 16/4885INPPL1 639/4885INPP5A 992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.