Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.42 |
| ▸ | ABAT | P80404 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28845216 | 0.92 | ALDH1A1 (0.50) | ALDH1A1CYP2A6CYP3A4TSHRDRD1 | |
| SCHEMBL16202966 | 0.90 | ALDH1A1 (0.45) | ALDH1A1CYP2A6CYP3A4TSHRDRD1 | |
| SCHEMBL28443438 | 0.87 | ALDH1A1 (0.47) | ALDH1A1CYP2A6CYP3A4TSHRDRD1 | |
| SCHEMBL6260382 | 0.82 | ALDH1A1 (0.47) | ALDH1A1CYP2A6CYP3A4TSHRDRD1 | |
| SCHEMBL31416540 | 0.82 | CA2 (0.57) | ALDH1A1CYP2A6CYP3A4TSHRDRD1 | |
| SCHEMBL3514847 | 0.82 | SRC (0.61) | ALDH1A1CYP2A6DRD1ALDH1A3STS | |
| SCHEMBL13858750 | 0.82 | ALDH1A1 (0.56) | ALDH1A1CYP2A6CYP3A4TSHRDRD1 | |
| SCHEMBL21800987 | 0.82 | ALDH1A1 (0.50) | ALDH1A1CYP2A6DRD1ALDH1A3STS | |
| SCHEMBL29153363 | 0.80 | TDP1 (0.52) | ALDH1A1CYP2A6DRD1ALDH1A3STS | |
| SCHEMBL19949867 | 0.80 | ALDH1A1 (0.40) | ALDH1A1CYP2A6CYP3A4TSHRDRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113444258-A | Preparation method and application of phosphorus-containing covalent porous material with flame retardant property | 河北工业大学 | 2021-09-28 | — | — | CN | claimed |
| CN-117003792-A | P-hydroxybenzaldehyde compound and method for preparing octreotide with assistance of p-hydroxybenzaldehyde compound | 西北工业大学 | 2023-11-07 | — | — | CN | disclosed |
| CN-113444258-B | Preparation method and application of phosphorus-containing covalent porous material with flame retardant property | 河北工业大学（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-113444258-A | Preparation method and application of phosphorus-containing covalent porous material with flame retardant property | 河北工业大学 | 2021-09-28 | — | — | CN | disclosed |
| US-9872911-B2 | Alpha-aminoamidine polymers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-01-23 | — | — | US | disclosed |
| US-20140322309-A1 | ALPHA-AMINOAMIDINE POLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLO (US) | 2014-10-30 | — | — | US | disclosed |
| WO-2013090861-A1 | ALPHA-AMINOAMIDINE POLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-06-20 | — | — | WO | disclosed |
| US-20100285601-A1 | METHOD OF ELECTRICALLY DETECTING A NUCLEIC ACID MOLECULE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-11-11 | — | — | US | disclosed |
| US-20100194409-A1 | METHOD OF ELECTRICALLY DETECTING A BIOLOGICAL ANALYTE MOLECULE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-08-05 | — | — | US | disclosed |
| US-7572795-B2 | Pyrrolotriazine aniline prodrug compounds useful as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-08-11 | — | — | US | disclosed |
| US-20090156555-A1 | PYRROLOTRIAZINE ANILINE PRODRUG COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2009-06-18 | — | — | US | disclosed |
| WO-2009041917-A1 | METHOD OF ELECTRICALLY DETECTING A NUCLEIC ACID MOLECULE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2009-04-02 | — | — | WO | disclosed |
| EP-2001886-A2 | PYRROLOTRIAZINE ANILINE PRODRUG COMPOUNDS USEFUL AS KINASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2008-12-17 | — | — | EP | disclosed |
| WO-2008020813-A1 | METHOD OF ELECTRICALLY DETECTING A BIOLOGICAL ANALYTE MOLECULE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2008-02-21 | — | — | WO | disclosed |
| WO-2007103839-A2 | PYRROLOTRIAZINE ANILINE PRODRUG COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-09-13 | — | — | WO | disclosed |
| US-20070213300-A1 | PYRROLOTRIAZINE ANILINE PRODRUG COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156555-A1 | PYRROLOTRIAZINE ANILINE PRODRUG COMPOUNDS USEFUL AS KINASE INHIBITORS | CDK2, CDK3, CDK1 | ALDH1A1 3301/4885CYP2A6 1884/4885CYP3A4 1228/4885 |
| US-20140322309-A1 | ALPHA-AMINOAMIDINE POLYMERS AND USES THEREOF | AAAS, AADAT, INMT | ALDH1A1 257/4885CYP2A6 4509/4885CYP3A4 4192/4885 |
| US-20070213300-A1 | PYRROLOTRIAZINE ANILINE PRODRUG COMPOUNDS USEFUL AS KINASE INHIBITORS | CDK2, CDK3, CDK1 | ALDH1A1 3055/4885CYP2A6 2049/4885CYP3A4 1305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.