Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.86 |
| ▸ | MAOA | P21397 | 2/20 | 0.86 |
| ▸ | MAOB | P27338 | 2/20 | 0.86 |
| ▸ | CA12 | O43570 | 2/20 | 0.86 |
| ▸ | CA1 | P00915 | 2/20 | 0.86 |
| ▸ | CA2 | P00918 | 2/20 | 0.86 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.86 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.86 |
| ▸ | CA9 | Q16790 | 2/20 | 0.86 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.86 |
| ▸ | PKM | P14618 | 2/20 | 0.86 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.86 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.86 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.86 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.86 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.86 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.86 |
| ▸ | XDH | P47989 | 1/20 | 0.86 |
| ▸ | TNKS | O95271 | 7/20 | 0.83 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 7-Hydroxyflavone SCHEMBL312148 | 0.93 | CYP19A1 (1.00) | CYP19A1MAOAMAOBCA12CA1 | |
| 7-Hydroxyflavone SCHEMBL29678183 | 0.93 | CYP19A1 (1.00) | CYP19A1MAOAMAOBCA12CA1 | |
| 7-Hydroxyflavone SCHEMBL27789687 | 0.91 | CYP19A1 (0.97) | CYP19A1MAOAMAOBCA12CA1 | |
| 7-Hydroxyflavone SCHEMBL10808394 | 0.91 | CYP19A1 (0.97) | CYP19A1MAOAMAOBCA12CA1 | |
| SCHEMBL29773081 | 0.91 | TNKS (1.00) | CYP19A1MAOAMAOBCA12CA1 | |
| SCHEMBL127446 | 0.91 | TNKS (1.00) | CYP19A1MAOAMAOBCA12CA1 | |
| Flavone SCHEMBL27534477 | 0.90 | TNKS (0.85) | CYP19A1MAOAMAOBCA12CA1 | |
| SCHEMBL157723 | 0.90 | CYP3A4 (1.00) | CYP19A1MAOAMAOBCA12CA1 | |
| SCHEMBL31167385 | 0.90 | CYP3A4 (1.00) | CYP19A1MAOAMAOBCA12CA1 | |
| Flavone SCHEMBL14246840 | 0.90 | MAOB (0.78) | CYP19A1MAOAMAOBCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9238821-B2 | Metabolic engineering for plant disease resistance | THE SAMUEL ROBERTS NOBLE FOUNDATION, INC. (US) | 2016-01-19 | — | — | US | disclosed |
| US-20100319084-A1 | METABOLIC ENGINEERING FOR PLANT DISEASE RESISTANCE | THE SAMUEL ROBERTS NOBLE FOUNDATION | 2010-12-16 | — | — | US | disclosed |