Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | XPO1 | O14980 | 4/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3513942 | 0.84 | HCAR2 (0.53) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL5070247 | 0.82 | HCAR2 (0.38) | HCAR2KEAP1NFE2L2 | |
| SCHEMBL178194 | 0.82 | HCAR2 (0.80) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL3400712 | 0.82 | HCAR2 (0.38) | HCAR2KEAP1NFE2L2 | |
| SCHEMBL3400715 | 0.82 | HCAR2 (0.38) | HCAR2KEAP1NFE2L2 | |
| SCHEMBL177748 | 0.82 | HCAR2 (0.80) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL177747 | 0.82 | HCAR2 (0.80) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL9241495 | 0.81 | HCAR2 (0.50) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL7571840 | 0.81 | HCAR2 (0.59) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL3514185 | 0.81 | HCAR2 (0.59) | HCAR2CA12AKR1B10CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236917-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20100240855-A1 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |