Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | VDR | P11473 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2353516 | 0.79 | ALDH1A1 (0.52) | ALDH1A1GAAKMT2AMAPTKDM4E | |
| SCHEMBL3289289 | 0.77 | ALDH1A1 (0.50) | ALDH1A1GAAKMT2AMAPTKDM4E | |
| SCHEMBL8223005 | 0.76 | ALDH1A1 (0.53) | ALDH1A1GAAKMT2AMAPTKDM4E | |
| SCHEMBL20768726 | 0.75 | GAA (0.56) | ALDH1A1GAAKMT2AMAPTKDM4E | |
| SCHEMBL262472 | 0.75 | GAA (0.56) | ALDH1A1GAAKMT2AMAPTKDM4E | |
| SCHEMBL30767916 | 0.75 | ALDH1A1 (1.00) | ALDH1A1GAAKMT2AMAPTKDM4E | |
| SCHEMBL1715729 | 0.75 | ALDH1A1 (1.00) | ALDH1A1GAAKMT2AMAPTKDM4E | |
| SCHEMBL4862857 | 0.75 | GAA (0.66) | ALDH1A1GAAKMT2AMAPTKDM4E | |
| SCHEMBL30226348 | 0.75 | GAA (0.66) | ALDH1A1GAAKMT2AMAPTKDM4E | |
| SCHEMBL28520455 | 0.74 | ALDH1A1 (0.47) | ALDH1A1GAAKMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11780935-B2 | Mutant antibodies and conjugation thereof | PFIZER HEALTHCARE IRELAND (IE) | 2023-10-10 | — | — | US | disclosed |
| US-20210147576-A1 | MUTANT ANTIBODIES AND CONJUGATION THEREOF | PFIZER HEALTHCARE IRELAND (IE) | 2021-05-20 | — | — | US | disclosed |
| EP-1589999-B1 | POLYVINYLETHERS FOR DELIVERY OF POLYNUCLEOTIDES TO MAMMALIAN CELLS | ARROWHEAD PHARMACEUTICALS INC (US) | 2018-09-19 | — | — | EP | disclosed |
| US-7682626-B2 | Polyvinylethers for delivery of polynucleotides to mammalian cells | ROCHE MADISON INC. (US) | 2010-03-23 | — | — | US | disclosed |
| EP-1589999-A2 | POLYVINYLETHERS FOR DELIVERY OF POLYNUCLEOTIDES TO MAMMALIAN CELLS | Mirus Corporation (US) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004072249-A2 | POLYVINYLETHERS FOR DELIVERY OF POLYNUCLEOTIDES TO MAMMALIAN CELLS | MIRUS CORPORATION (US) | 2004-08-26 | — | — | WO | disclosed |
| US-20040156909-A1 | Polyvinylethers for delivery of polynucleotides to mammalian cells | Arrowhead Pharmaceuticals, Inc. | 2004-08-12 | — | — | US | disclosed |
| WO-1995025090-A1 | CYCLIC N-ALKENYLOXYIMIDES AND A METHOD FOR THE PREPARATION OF CYCLIC N-ALKENYLOXYIMIDES, THE CORRESPONDING CYCLIC N-ALKOXYIMIDES AND O-ALKOXYAMINES | DSM N.V. (NL) | 1995-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210147576-A1 | MUTANT ANTIBODIES AND CONJUGATION THEREOF | IGLV6-57, IGSF11, F13B | ALDH1A1 3691/4885GAA 2376/4885KMT2A 1718/4885 |
| US-11780935-B2 | Mutant antibodies and conjugation thereof | IGLV6-57, IGSF11, F13B | ALDH1A1 3744/4885GAA 2394/4885KMT2A 1715/4885 |
| US-20040156909-A1 | Polyvinylethers for delivery of polynucleotides to mammalian cells | POLI, POLRMT, PABPC4 | ALDH1A1 4681/4885GAA 1321/4885KMT2A 3162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.