SCHEMBL3515939

SCHEMBL3515939

C=CC(=O)OCCCc1ccccc1[SiH](OC)OC

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.47
THRA P10827 1/20 0.43
TSHR P16473 5/20 0.43
HPGD P15428 1/20 0.43
ALDH1A1 P00352 4/20 0.42
CYP3A4 P08684 1/20 0.42
AKR1B10 O60218 5/20 0.40
AKR1B1 P15121 5/20 0.40
TP53 P04637 2/20 0.39
HIF1A Q16665 2/20 0.39
HSD17B10 Q99714 1/20 0.39
ALOX5 P09917 4/20 0.36
LMNA P02545 1/20 0.33
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15361861 0.96 THRB (0.46) THRBTHRATSHRHPGDALDH1A1
SCHEMBL15361878 0.87 THRB (0.45) THRBTHRATSHRHPGDALDH1A1
SCHEMBL15361914 0.87 TSHR (0.48) THRBTHRATSHRHPGDALDH1A1
SCHEMBL235467 0.83 THRB (0.41) THRBTHRATSHRHPGDALDH1A1
SCHEMBL3517115 0.82 TDP1 (0.44) THRBTSHRALDH1A1CYP3A4AKR1B10
SCHEMBL27759953 0.79 THRB (0.53) THRBTHRATSHRHPGDALDH1A1
SCHEMBL15361902 0.78 TDP1 (0.46) THRBTHRATSHRALDH1A1CYP3A4
SCHEMBL27530889 0.77 THRB (0.54) THRBTHRATSHRHPGDALDH1A1
SCHEMBL10459225 0.76 THRB (0.47) THRBTHRATSHRHPGDALDH1A1
SCHEMBL1779005 0.76 THRB (0.52) THRBTHRATSHRHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108368263-B Resin, paste, laminate obtained using the same, and method for producing the laminate 东丽株式会社 2021-03-12 CN disclosed
EP-2228362-B1 4-HYDROXYPHENYLALKYLAMINE DERIVATIVE DOW CORNING TORAY CO LTD (JP) 2017-06-07 EP disclosed
US-20160299376-A1 LIQUID CRYSTAL DISPLAY DEVICE, RADIATION-SENSITIVE RESIN COMPOSITION, INTERLAYER INSULATING FILM, METHOD FOR PRODUCING INTERLAYER INSULATING FILM, AND METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE JSR CORPORATION (JP) 2016-10-13 US disclosed
EP-2228362-A1 4-HYDROXYPHENYLALKYLAMINE DERIVATIVE Dow Corning Toray Co., Ltd. (JP) 2010-09-15 EP disclosed
US-7192986-B2 Inorganic compound sol modified by organic compound CATALYSTS & CHEMICALS INDUSTRIES CO., LTD. (JP) 2007-03-20 US disclosed
US-20030193037-A1 INORGANIC COMPOUND SOL MODIFIED BY ORGANIC COMPOUND CATALYSTS & CHEMICALS INDUSTRIES CO., LTD. (JP) 2003-10-16 US disclosed