Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15361902 | 0.96 | TDP1 (0.46) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL8666446 | 0.88 | TDP1 (0.43) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL15361896 | 0.87 | TSHR (0.46) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL2345681 | 0.87 | THRB (0.43) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL9715816 | 0.85 | TDP1 (0.45) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL237532 | 0.83 | POLB (0.36) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL8670042 | 0.82 | THRB (0.43) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL3515939 | 0.82 | THRB (0.47) | TSHRTHRBLMNAAKR1B10AKR1B1 | |
| SCHEMBL27637386 | 0.79 | TSHR (0.54) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL15361861 | 0.78 | THRB (0.46) | TDP1TSHRTHRBAKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368263-B | Resin, paste, laminate obtained using the same, and method for producing the laminate | 东丽株式会社 | 2021-03-12 | — | — | CN | disclosed |
| EP-2228362-B1 | 4-HYDROXYPHENYLALKYLAMINE DERIVATIVE | DOW CORNING TORAY CO LTD (JP) | 2017-06-07 | — | — | EP | disclosed |
| US-20160299376-A1 | LIQUID CRYSTAL DISPLAY DEVICE, RADIATION-SENSITIVE RESIN COMPOSITION, INTERLAYER INSULATING FILM, METHOD FOR PRODUCING INTERLAYER INSULATING FILM, AND METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE | JSR CORPORATION (JP) | 2016-10-13 | — | — | US | disclosed |
| US-8624064-B2 | 4-hydroxyphenylalkylamine derivative | DOW CORNING TORAY COMPANY, LTD. (JP) | 2014-01-07 | — | — | US | disclosed |
| US-20100280188-A1 | 4-HYDROXYPHENYLALKYLAMINE DERIVATIVE | DOW TORAY CO., LTD. (JP) | 2010-11-04 | — | — | US | disclosed |
| EP-2228362-A1 | 4-HYDROXYPHENYLALKYLAMINE DERIVATIVE | Dow Corning Toray Co., Ltd. (JP) | 2010-09-15 | — | — | EP | disclosed |
| US-7192986-B2 | Inorganic compound sol modified by organic compound | CATALYSTS & CHEMICALS INDUSTRIES CO., LTD. (JP) | 2007-03-20 | — | — | US | disclosed |
| US-20030193037-A1 | INORGANIC COMPOUND SOL MODIFIED BY ORGANIC COMPOUND | CATALYSTS & CHEMICALS INDUSTRIES CO., LTD. (JP) | 2003-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280188-A1 | 4-HYDROXYPHENYLALKYLAMINE DERIVATIVE | HRH3, HRH4, PAH | TDP1 2438/4885POLB 2102/4885APEX1 1929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.