SCHEMBL3515976

SCHEMBL3515976

Cn1cnc2c1CCNC2

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 3/20 0.34
DRD4 P21917 1/20 0.34
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
MCHR1 Q99705 4/20 0.32
HTR2A P28223 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1993713 0.98 HTR2C (0.33) HTR2CDRD4PDCD1CD274MCHR1
SCHEMBL29837287 0.87
SCHEMBL3516499 0.86 HTR2C (0.39) HTR2CDRD4HTR2A
SCHEMBL11517457 0.85 HTR2C (0.34) HTR2CDRD4HTR2A
Hydrochloric Acid SCHEMBL1995042 0.83 HTR2C (0.33) HTR2CDRD4
SCHEMBL31651687 0.82
SCHEMBL16788741 0.77 HTR2C (0.32) HTR2C
Hydrochloric Acid SCHEMBL18953822 0.76 CPB2 (0.40) HTR2C
SCHEMBL21363443 0.75 SRC (0.38) HTR2C
SCHEMBL13506399 0.74 MEN1 (0.39) PDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115925702-B Purification method of imidazo [4,5-C ] pyridine derivative and imidazo [4,5-C ] pyridine derivative 江西凌富生物科技有限公司 2025-04-25 CN claimed
CN-115925702-A Method for purifying imidazo [4,5-C ] pyridine derivative and imidazo [4,5-C ] pyridine derivative 江西凌富生物科技有限公司 2023-04-07 CN claimed
CN-110950886-A Method for synthesizing 1-methyl-imidazole-2-methyl formate derivative 苏州莱克施德药业有限公司 2020-04-03 CN claimed
EP-4735430-A1 MALT1 INHIBITORS Janssen Pharmaceutica NV (BE) 2026-05-06 EP disclosed
US-20260069605-A1 KRAS INHIBITORS INCYTE CORP (US) 2026-03-12 US disclosed
US-20260035388-A1 HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS INCYTE CORP (US) 2026-02-05 US disclosed
US-20260034126-A1 KRAS INHIBITORS INCYTE CORP (US) 2026-02-05 US disclosed
US-20250368641-A1 QUINOLINE COMPOUNDS AS INHIBITORS OF KRAS INCYTE CORP (US) 2025-12-04 US disclosed
US-12466822-B2 Heterocyclic compounds as immunomodulators INCYTE CORPORATION (US) 2025-11-11 US disclosed
US-20250325660-A1 IMMUNOMODULATOR COMPOUNDS AND METHODS OF USE INCYTE CORP (US) 2025-10-23 US disclosed
US-20250320201-A1 COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS AGIOS PHARMACEUTICALS INC (US) 2025-10-16 US disclosed
US-8404674-B2 Substituted 9H-purin-2-YL compounds, compositions thereof and uses thereof BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-03-26 US disclosed
US-8258129-B2 4-heterocycloalkylpyri(mi)dines, process for the preparation thereof and their use as medicaments BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2012-09-04 US disclosed
US-20100311721-A1 COMPOUNDS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-12-09 US disclosed
EP-2134723-A1 9H- PURINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PROLIFERATIVE DISEASES Boehringer Ingelheim International GmbH (DE) 2009-12-23 EP disclosed
US-20090203673-A1 4-HETEROCYCLOALKYLPYRI(MI)DINES, PROCESS FOR THE PREPARATION THEREOF AND THEIR USE AS MEDICAMENTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-08-13 US disclosed
EP-2041132-A2 NEW COMPOUNDS Boehringer Ingelheim International GmbH (DE) 2009-04-01 EP disclosed
WO-2008107444-A1 9H- PURINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PROLIFERATIVE DISEASES BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2008-09-12 WO disclosed
WO-2008003766-A2 4-HETER0CYCL0ALKYLPYRI(MI)DINES, PROCESS FOR THE PREPARATION THEREOF AND THEIR USE AS MEDICAMENTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2008-01-10 WO disclosed
US-4223146-A ANTIULCER AGENTS FARMITALIA CARLO ERBA S.P.A. (IT) 1980-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100311721-A1 COMPOUNDS CCNA1, MKI67, CCNT1 HTR2C 2726/4885DRD4 1448/4885PDCD1 787/4885
US-20250325660-A1 IMMUNOMODULATOR COMPOUNDS AND METHODS OF USE CD274, PDCD1LG2, PDCD1 HTR2C 2665/4885DRD4 2634/4885PDCD1 3/4885
US-12466822-B2 Heterocyclic compounds as immunomodulators CD74, IL2, ICOS HTR2C 2942/4885DRD4 3254/4885PDCD1 157/4885
US-20260035388-A1 HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS IL2, IL4, NFATC1 HTR2C 914/4885DRD4 3040/4885PDCD1 167/4885
US-20260034126-A1 KRAS INHIBITORS KRAS, NRAS, HRAS HTR2C 3074/4885DRD4 3850/4885PDCD1 3233/4885
US-20250320201-A1 COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS PAH, KDM8, PHF8 HTR2C 2699/4885DRD4 3751/4885PDCD1 4471/4885
US-20250368641-A1 QUINOLINE COMPOUNDS AS INHIBITORS OF KRAS KRAS, NRAS, HRAS HTR2C 4654/4885DRD4 4536/4885PDCD1 2899/4885
US-20260069605-A1 KRAS INHIBITORS KRAS, NRAS, HRAS HTR2C 4063/4885DRD4 2655/4885PDCD1 2508/4885
US-20090203673-A1 4-HETEROCYCLOALKYLPYRI(MI)DINES, PROCESS FOR THE PREPARATION THEREOF AND THEIR USE AS MEDICAMENTS CCNI, MKI67, CCNA1 HTR2C 1296/4885DRD4 660/4885PDCD1 970/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.