SCHEMBL351709

SCHEMBL351709

[CH2][C@H](N)Cc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.64
SLC6A2 P23975 2/20 0.58
TAAR1 Q96RJ0 2/20 0.58
MAOA P21397 1/20 0.58
SLC6A4 P31645 1/20 0.58
SLC6A3 Q01959 1/20 0.58
SIGMAR1 Q99720 1/20 0.58
CYP2A6 P11509 1/20 0.58
ADORA2A P29274 1/20 0.58
ADORA1 P30542 1/20 0.58
ANPEP P15144 2/20 0.54
CYP2D6 P10635 1/20 0.54
ALPI P09923 1/20 0.52
PKM P14618 1/20 0.52
PTGS1 P23219 1/20 0.52
XIAP P98170 1/20 0.52
SLC7A5 Q01650 1/20 0.52
LAP3 P28838 3/20 0.48
SLC1A3 P43003 1/20 0.47
SLC1A2 P43004 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1785509 1.00 EPHX1 (0.64) EPHX1SLC6A2TAAR1MAOASLC6A4
SCHEMBL6931237 1.00 EPHX1 (0.64) EPHX1SLC6A2TAAR1MAOASLC6A4
SCHEMBL28656 0.78 EPHX1 (1.00) EPHX1SLC6A2TAAR1MAOASLC6A4
SCHEMBL9536448 0.78 EPHX1 (0.70) EPHX1SLC6A2TAAR1MAOASLC6A4
SCHEMBL3588912 0.78 EPHX1 (0.55) EPHX1SLC6A2TAAR1MAOASLC6A4
SCHEMBL24017042 0.78 EPHX1 (0.70) EPHX1SLC6A2TAAR1MAOASLC6A4
SCHEMBL708446 0.78 EPHX1 (0.70) EPHX1SLC6A2TAAR1MAOASLC6A4
SCHEMBL1287678 0.78 EPHX1 (0.55) EPHX1SLC6A2TAAR1MAOASLC6A4
SCHEMBL9627376 0.77 EPHX1 (0.54) EPHX1SLC6A2TAAR1MAOASLC6A4
SCHEMBL2845167 0.77 EPHX1 (0.54) EPHX1SLC6A2TAAR1MAOASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230218562-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-07-13 US claimed
US-20210113514-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS., LTD. 2021-04-22 US claimed
US-10888542-B2 Aminocarbonylcarbamate compounds SK BIOPHARMACEUTICALS CO., LTD. (KR) 2021-01-12 US claimed
US-20200046674-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2020-02-13 US claimed
US-9833432-B2 Aminocarbonylcarbamate compounds SK BIOPHARMACEUTICALS CO., LTD. (KR) 2017-12-05 US claimed
EP-3110792-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK Biopharmaceuticals Co., Ltd. (KR) 2017-01-04 EP claimed
US-20160303067-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. 2016-10-20 US claimed
US-9403761-B2 Aminocarbonylcarbamate compounds SK BIOPHARMACEUTICALS CO., LTD. (KR) 2016-08-02 US claimed
WO-2015130121-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2015-09-03 WO claimed
US-20150246874-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2015-09-03 US claimed
EP-1572892-A4 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS BRISTOL MYERS SQUIBB CO (US) 2007-08-22 EP claimed
EP-1615653-A2 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS Bristol-Myers Squibb Company (US) 2006-01-18 EP claimed
EP-1572892-A2 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS Bristol-Myers Squibb Company (US) 2005-09-14 EP claimed
CN-1630709-A Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions BRISTOL MYERS SQUIBB CO (US) 2005-06-22 CN claimed
WO-2004094461-A2 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS BRISTOL-MYERS SQUIBB COMPANY (US) 2004-11-04 WO claimed
US-20040127423-A1 Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions BRISTOL-MYERS SQUIBB COMPANY 2004-07-01 US claimed
US-20030195157-A1 Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions BRISTOL-MYERS SQUIBB COMPANY 2003-10-16 US claimed
WO-2003033671-A2 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS BRISTOL-MYERS SQUIBB COMPANY (US) 2003-04-24 WO claimed
EP-0296059-B1 TRIPEPTIDES WITH A POLYCYCLIC NITROGEN STRUSTURE, THEIR PROCESS OF PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS THEREOF ADIR ET COMPAGNIE (FR) 1992-03-18 EP claimed
US-5047400-A Treatment of infection; antitumor agents ADIR ET CIE (FR) 1991-09-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150246874-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 EPHX1 3504/4885SLC6A2 2/4885TAAR1 79/4885
US-10888542-B2 Aminocarbonylcarbamate compounds SLC6A3, SLC6A2, SLC6A4 EPHX1 3504/4885SLC6A2 2/4885TAAR1 79/4885
US-20030195157-A1 Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions GLP1R, IAPP, GIPR EPHX1 4040/4885SLC6A2 4544/4885TAAR1 4360/4885
US-20040127423-A1 Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions GLP1R, IAPP, GIPR EPHX1 4040/4885SLC6A2 4544/4885TAAR1 4360/4885
US-20160303067-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 EPHX1 3504/4885SLC6A2 2/4885TAAR1 79/4885
US-20210113514-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 EPHX1 3504/4885SLC6A2 2/4885TAAR1 79/4885
US-20200046674-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 EPHX1 3504/4885SLC6A2 2/4885TAAR1 79/4885
US-20230218562-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 EPHX1 3504/4885SLC6A2 2/4885TAAR1 79/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.