⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19645307 | 1.00 | — | — | |
| SCHEMBL5351420 | 1.00 | — | — | |
| SCHEMBL13889160 | 1.00 | — | — | |
| SCHEMBL1672698 | 1.00 | — | — | |
| SCHEMBL191998 | 1.00 | — | — | |
| SCHEMBL1983990 | 1.00 | CYP2C9 (0.39) | — | |
| SCHEMBL285299 | 1.00 | — | — | |
| SCHEMBL36515 | 1.00 | — | — | |
| Water SCHEMBL227534 | 0.94 | LMNA (0.37) | — | |
| Cyclopropane SCHEMBL483844 | 0.89 | TSHR (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2689013-A1 | COMPOSITIONS FOR INHIBITING GENE EXPRESSION AND USES THEREOF | Idera Pharmaceuticals, Inc. (US) | 2014-01-29 | — | — | EP | disclosed |
| WO-2012135152-A1 | COMPOSITIONS FOR INHIBITING GENE EXPRESSION AND USES THEREOF | IDERA PHARMACEUTICALS, INC. (US) | 2012-10-04 | — | — | WO | disclosed |
| US-20120016004-A1 | COMPOSITIONS FOR INHIBITING GENE EXPRESSION AND USES THEREOF | IDERA PHARMACEUTICALS, INC. | 2012-01-19 | — | — | US | disclosed |