Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3517874 | 1.00 | CA1 (0.45) | CA1CA2MAPK1ACE2FDPS | |
| SCHEMBL3516726 | 0.87 | CHRM1 (0.41) | CA1ACE2FDPSSLC1A3SLC1A2 | |
| SCHEMBL21436874 | 0.85 | CA1 (0.57) | CA1ACE2FDPSFFAR1FFAR4 | |
| SCHEMBL21436875 | 0.85 | CA1 (0.57) | CA1ACE2FDPSFFAR1FFAR4 | |
| SCHEMBL28323830 | 0.83 | CA1 (0.55) | CA1ACE2FDPSFFAR1FFAR4 | |
| SCHEMBL10481806 | 0.82 | CA1 (0.44) | CA1CA2MAPK1ACE2FDPS | |
| SCHEMBL8169390 | 0.80 | CA1 (0.47) | CA1CA2MAPK1ACE2FDPS | |
| SCHEMBL10451985 | 0.80 | CA1 (0.42) | CA1CA2MAPK1ACE2FDPS | |
| SCHEMBL3515517 | 0.78 | ALDH1A1 (0.32) | ACE2 | |
| SCHEMBL3515511 | 0.78 | ALDH1A1 (0.32) | ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236917-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20100240855-A1 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |