Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9318291 | 0.95 | TSHR (0.33) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| Alcohol SCHEMBL7187474 | 0.86 | TSHR (0.35) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL45388 | 0.83 | TSHR (0.41) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL4556468 | 0.83 | TSHR (0.41) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL1539720 | 0.83 | TSHR (0.35) | TSHRALDH1A1THRB | |
| SCHEMBL24603372 | 0.83 | TSHR (0.41) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL8343493 | 0.83 | TSHR (0.35) | TSHRALDH1A1THRB | |
| SCHEMBL19286829 | 0.83 | SMN1; SMN2 (0.32) | TSHRALDH1A1SMN1; SMN2 | |
| Allyl Alcohol SCHEMBL27586989 | 0.81 | TSHR (0.50) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL7127962 | 0.81 | TSHR (0.33) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1219953-A | Fabric softening compound/composition | PROCTER & GAMBLE (US) | 1999-06-16 | — | — | CN | claimed |
| CN-1195369-A | Concentrated and stable fabric softening compositions | PROCTER & GAMBLE (US) | 1998-10-07 | — | — | CN | claimed |
| JP-62199641-A | — | — | None | — | — | JP | disclosed |
| JP-2296884-A | — | — | None | — | — | JP | disclosed |
| JP-5222333-A | — | — | None | — | — | JP | disclosed |
| JP-4335072-A | — | — | None | — | — | JP | disclosed |
| JP-60199049-A | — | — | None | — | — | JP | disclosed |
| US-8183275-B2 | Substituted imidazoles as bombesin receptor subtype-3 modulators | MERCK SHARP & DOHME CORP. (US) | 2012-05-22 | — | — | US | disclosed |
| US-20100204236-A1 | Substituted imidazoles as bombesin receptor subtype-3 modulators | MERCK SHARP & DOHME CORP. | 2010-08-12 | — | — | US | disclosed |
| EP-2083623-A1 | SUBSTITUTED IMIDAZOLES AS BOMBESIN RECEPTOR SUBTYPE-3 MODULATORS | Merck & Co., Inc. (US) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008051405-A1 | SUBSTITUTED IMIDAZOLES AS BOMBESIN RECEPTOR SUBTYPE-3 MODULATORS | MERCK & CO., INC. (US) | 2008-05-02 | — | — | WO | disclosed |
| CN-1195369-A | Concentrated and stable fabric softening compositions | PROCTER & GAMBLE (US) | 1998-10-07 | — | — | CN | disclosed |
| JP-H05222333-A | PRINTING INK BINDER AND PRINTING INK COMPOSITION | ARAKAWA CHEM IND CO LTD | 1993-08-31 | — | — | JP | disclosed |
| JP-H04335072-A | COATING MATERIAL | ARAKAWA CHEM IND CO LTD | 1992-11-24 | — | — | JP | disclosed |
| JP-H02296884-A | POLYURETHANE ADHESIVE | CHISSO CORP | 1990-12-07 | — | — | JP | disclosed |
| JP-S62199641-A | POLYVINYL CHLORIDE RESIN COMPOSITION | CHISSO CORP | 1987-09-03 | — | — | JP | disclosed |
| JP-S60199049-A | POLYESTER PLASTICIZER | CHISSO CORP | 1985-10-08 | — | — | JP | disclosed |
| US-4150237-A | INTERMEDIATES IN THE FORMATION OF EPOXIDES | THE DOW CHEMICAL COMPANY (US) | 1979-04-17 | — | — | US | disclosed |
| US-4126746-A | Halohydrin thioethers and method of preparation | THE DOW CHEMICAL COMPANY (US) | 1978-11-21 | — | — | US | disclosed |
| US-3959103-A | Photocuring of unsaturated polyester/polythiol compositions | W. R. GRACE & CO. (US) | 1976-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204236-A1 | Substituted imidazoles as bombesin receptor subtype-3 modulators | BRS3, GPR119, GIPR | TSHR 238/4885ALDH1A1 4808/4885TP53 4749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.