Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45388 | 0.91 | TSHR (0.41) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL3518097 | 0.86 | TSHR (0.33) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL9318291 | 0.86 | TSHR (0.33) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL24603372 | 0.85 | TSHR (0.41) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL4556468 | 0.85 | TSHR (0.41) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL31417819 | 0.82 | TSHR (0.32) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL5006489 | 0.80 | — | — | |
| SCHEMBL5006496 | 0.80 | — | — | |
| SCHEMBL7127962 | 0.79 | TSHR (0.33) | TSHRALDH1A1 | |
| Acetic Acid SCHEMBL9219720 | 0.77 | ALDH1A1 (0.39) | TSHRALDH1A1TP53CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140884-B1 | PROCESS FOR PRODUCTION OF AN OXETANE | PERSTORP AB (SE) | 2003-09-10 | — | — | EP | claimed |