Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 16/20 | 0.72 |
| ▸ | PDE4A | P27815 | 4/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1223262 | 0.86 | PGR (0.55) | PGRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5225371 | 0.85 | PGR (1.00) | PGRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1222740 | 0.85 | PGR (0.55) | PGRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7128459 | 0.78 | PGR (0.44) | PGRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3521215 | 0.74 | PGR (0.56) | PGRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3521249 | 0.73 | PGR (0.61) | PGRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3522548 | 0.72 | PGR (0.56) | PGRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5225933 | 0.70 | PGR (0.65) | PGRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3521989 | 0.68 | PGR (1.00) | PGR | |
| SCHEMBL6409727 | 0.68 | PGR (1.00) | PGRPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645761-B2 | Indoline derivatives | WYETH (US) | 2010-01-12 | — | — | US | disclosed |