Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 15/20 | 0.56 |
| ▸ | FNTB | P49356 | 15/20 | 0.56 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4287009 | 0.89 | FNTA (0.56) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL3501050 | 0.81 | FNTA (0.84) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL4278951 | 0.74 | FNTA (0.55) | FNTAFNTBPGGT1BCYP3A4RORC | |
| SCHEMBL6173299 | 0.74 | FNTA (0.82) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL4562525 | 0.73 | FNTA (1.00) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL4562526 | 0.73 | FNTA (1.00) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL4282437 | 0.73 | FNTA (0.51) | FNTAFNTBPGGT1BCYP3A4RORC | |
| SCHEMBL4285788 | 0.72 | FNTA (0.60) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL6172871 | 0.71 | FNTA (0.60) | FNTAFNTBPGGT1B | |
| SCHEMBL7815392 | 0.71 | FNTA (0.84) | FNTAFNTBPGGT1BRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155197-A2 | TREATMENT OF LYSOSOMAL STORAGE DISEASES | Link Medicine Corporation (US) | 2010-02-24 | — | — | EP | claimed |
| WO-2008112525-A2 | TREATMENT OF LYSOSOMAL STORAGE DISEASES | LINK MEDICINE CORPORATION (US) | 2008-09-18 | — | — | WO | claimed |
| WO-2008137692-A1 | TREATMENT OF SYNUCLEINOPATHIES | LINK MEDICINE CORPORATION (US) | 2008-11-13 | — | — | WO | disclosed |